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Property and Equipment - Summary of Property and Equipment (Detail) - USD ($)
$ in Thousands
Mar. 31, 2023
Dec. 31, 2022
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 19,464 $ 20,613
Less accumulated depreciation 10,857 10,956
Property and equipment, net 8,607 9,657
Furniture and Fixtures [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 936 868
Laboratory Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 15,372 16,416
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 440 384
Computer Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 677 677
Computer Software [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 553 553
Construction in Progress [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 1,486 $ 1,715