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Condensed Consolidated Statements of Changes in Stockholders' Equity - USD ($) $ in Thousands | Total | At-the-Market Public Offering [Member] | Private Placement [Member] | Common Stock [Member] | Common Stock [Member] At-the-Market Public Offering [Member] | Common Stock [Member] Private Placement [Member] | Additional Paid in Capital [Member] | Additional Paid in Capital [Member] At-the-Market Public Offering [Member] | Additional Paid in Capital [Member] Private Placement [Member] | Accumulated Other Comprehensive Income (Loss) [Member] | Accumulated Deficit [Member]
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2023 | $ 126,481 |  |  | $ 20 |  |  | $ 785,199 |  |  | $ 15 | $ (658,753)
Beginning balance, units at Dec. 31, 2023 |  |  |  | 20,386,606 |  |  |  |  |  |  |
Issuance of common stock, net of issuance costs |  | $ 3,056 | $ 89,454 |  | $ 1 | $ 17 |  | $ 3,055 | $ 89,437 |  |
Issuance of common stock, net of issuance costs, units |  |  |  |  | 350,664 | 16,973,103 |  |  |  |  |
Issuance of pre-funded warrants in public offering/private placement | 14,293 |  |  |  |  |  | 14,293 |  |  |  |
Vesting of restricted stock, units |  |  |  | 98,677 |  |  |  |  |  |  |
Exercises of common stock options | 151 |  |  |  |  |  | 151 |  |  |  |
Exercises of common stock options, units |  |  |  | 24,639 |  |  |  |  |  |  |
Unrealized loss on available-for-sale securities | (19) |  |  |  |  |  |  |  |  | (19) |
Equity-based compensation expense | 1,611 |  |  |  |  |  | 1,611 |  |  |  |
Net loss | (24,303) |  |  |  |  |  |  |  |  |  | (24,303)
Ending balance at Mar. 31, 2024 | 210,724 |  |  | $ 38 |  |  | 893,746 |  |  | (4) | (683,056)
Ending balance, units at Mar. 31, 2024 |  |  |  | 37,833,689 |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2023 | 126,481 |  |  | $ 20 |  |  | 785,199 |  |  | 15 | (658,753)
Beginning balance, units at Dec. 31, 2023 |  |  |  | 20,386,606 |  |  |  |  |  |  |
Unrealized loss on available-for-sale securities | (30) |  |  |  |  |  |  |  |  |  |
Net loss | (49,375) |  |  |  |  |  |  |  |  |  |
Ending balance at Jun. 30, 2024 | 193,245 |  |  | $ 39 |  |  | 901,349 |  |  | (15) | (708,128)
Ending balance, units at Jun. 30, 2024 |  |  |  | 38,551,059 |  |  |  |  |  |  |
Beginning balance at Mar. 31, 2024 | 210,724 |  |  | $ 38 |  |  | 893,746 |  |  | (4) | (683,056)
Beginning balance, units at Mar. 31, 2024 |  |  |  | 37,833,689 |  |  |  |  |  |  |
Issuance of common stock, net of issuance costs |  | 5,357 |  |  | $ 1 |  |  | 5,356 |  |  |
Issuance of common stock, net of issuance costs, units |  |  |  |  | 526,953 |  |  |  |  |  |
Vesting of restricted stock, units |  |  |  | 131,859 |  |  |  |  |  |  |
Exercises of common stock options | 10 |  |  |  |  |  | 10 |  |  |  |
Exercises of common stock options, units |  |  |  | 1,703 |  |  |  |  |  |  |
Issuance of common stock under employee stock purchase plan | 145 |  |  |  |  |  | 145 |  |  |  |
Issuance of common stock under employee stock purchase plan, units |  |  |  | 56,855 |  |  |  |  |  |  |
Unrealized loss on available-for-sale securities | (11) |  |  |  |  |  |  |  |  | (11) |
Equity-based compensation expense | 2,092 |  |  |  |  |  | 2,092 |  |  |  |
Net loss | (25,072) |  |  |  |  |  |  |  |  |  | (25,072)
Ending balance at Jun. 30, 2024 | 193,245 |  |  | $ 39 |  |  | 901,349 |  |  | (15) | (708,128)
Ending balance, units at Jun. 30, 2024 |  |  |  | 38,551,059 |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2024 | 137,246 |  |  | $ 40 |  |  | 920,609 |  |  | 47 | (783,450)
Beginning balance, units at Dec. 31, 2024 |  |  |  | 40,468,141 |  |  |  |  |  |  |
Issuance of common stock, net of issuance costs | 135,367 | $ 246 |  | $ 36 |  |  | 135,331 | $ 246 |  |  |
Issuance of common stock, net of issuance costs, units |  |  |  | 35,739,810 | 61,542 |  |  |  |  |  |
Issuance of pre-funded warrants in public offering/private placement | 52,590 |  |  |  |  |  | 52,590 |  |  |  |
Issuance of common stock in private placement for payment of developmental milestone consideration | 5,000 |  |  | $ 1 |  |  | 4,999 |  |  |  |
Issuance of common stock in private placement for payment of developmental milestone consideration, units |  |  |  | 975,496 |  |  |  |  |  |  |
Vesting of restricted stock, units |  |  |  | 247,970 |  |  |  |  |  |  |
Unrealized loss on available-for-sale securities | (45) |  |  |  |  |  |  |  |  | (45) |
Equity-based compensation expense | 3,341 |  |  |  |  |  | 3,341 |  |  |  |
Net loss | (39,282) |  |  |  |  |  |  |  |  |  | (39,282)
Ending balance at Mar. 31, 2025 | 294,463 |  |  | $ 77 |  |  | 1,117,116 |  |  | 2 | (822,732)
Ending balance, units at Mar. 31, 2025 |  |  |  | 77,492,959 |  |  |  |  |  |  |
Beginning balance at Dec. 31, 2024 | $ 137,246 |  |  | $ 40 |  |  | 920,609 |  |  | 47 | (783,450)
Beginning balance, units at Dec. 31, 2024 |  |  |  | 40,468,141 |  |  |  |  |  |  |
Exercises of common stock options, units | 2,733 |  |  |  |  |  |  |  |  |  |
Unrealized loss on available-for-sale securities | $ (85) |  |  |  |  |  |  |  |  |  |
Net loss | (78,762) |  |  |  |  |  |  |  |  |  |
Ending balance at Jun. 30, 2025 | 258,291 |  |  | $ 78 |  |  | 1,120,463 |  |  | (38) | (862,212)
Ending balance, units at Jun. 30, 2025 |  |  |  | 77,602,741 |  |  |  |  |  |  |
Beginning balance at Mar. 31, 2025 | 294,463 |  |  | $ 77 |  |  | 1,117,116 |  |  | 2 | (822,732)
Beginning balance, units at Mar. 31, 2025 |  |  |  | 77,492,959 |  |  |  |  |  |  |
Vesting of restricted stock, units |  |  |  | 32,189 |  |  |  |  |  |  |
Exercises of common stock options | 6 |  |  |  |  |  | 6 |  |  |  |
Exercises of common stock options, units |  |  |  | 2,733 |  |  |  |  |  |  |
Issuance of common stock under employee stock purchase plan | 197 |  |  | $ 1 |  |  | 196 |  |  |  |
Issuance of common stock under employee stock purchase plan, units |  |  |  | 74,860 |  |  |  |  |  |  |
Unrealized loss on available-for-sale securities | (40) |  |  |  |  |  |  |  |  | (40) |
Equity-based compensation expense | 3,145 |  |  |  |  |  | 3,145 |  |  |  |
Net loss | (39,480) |  |  |  |  |  |  |  |  |  | (39,480)
Ending balance at Jun. 30, 2025 | $ 258,291 |  |  | $ 78 |  |  | $ 1,120,463 |  |  | $ (38) | $ (862,212)
Ending balance, units at Jun. 30, 2025 |  |  |  | 77,602,741 |  |  |  |  |  |  |

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