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Acquisitions - Assets acquired and liabilities assumed (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
May 21, 2025
Sep. 30, 2025
Sep. 30, 2025
Liabilities Assumed      
Gain on bargain purchase     $ 187,907
ACELYRIN      
Assets Acquired      
Cash and cash equivalents $ 49,155    
Restricted cash 367    
Marketable securities 333,436    
Research and development prepaid expenses 958    
Prepaid credit voucher for clinical manufacturing 11,376    
Other prepaid expenses and current assets 8,081    
Restricted cash, non-current 220    
Property and equipment, net 420    
Intangible assets 50,959    
Operating lease right-of-use assets, net 4,349    
Other assets, non-current 744    
Total assets 460,065    
Liabilities Assumed      
Accounts payable (6,518)    
Research and development accrued expenses (3,546)    
Other accrued expenses and current liabilities (5,688)    
Operating lease liabilities, current (1,390)    
Operating lease liabilities, non-current (6,238)    
Deferred income tax liability (10,701)    
Total liabilities (34,081)    
Fair value of net assets 425,984    
Purchase consideration 238,077    
Gain on bargain purchase $ 187,907 $ 0 $ 187,900