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Commitments and Contingent Liabilities - Operating Leases (Details)
 1 Months Ended 12 Months Ended
Dec. 31, 2024
ft²
Jul. 31, 2023
USD ($)
ft²
Jan. 31, 2023
USD ($)
ft²
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Sep. 30, 2025
USD ($)
Jan. 31, 2025
USD ($)
Aug. 31, 2022
USD ($)
ft²
Lessee, Lease, Description [Line Items]                
Lease space | ft² 22,000             55,000
Tenant improvement allowance provided by lessor               $ 17,200,000
Tenant improvement allowance received       $ 16,700,000 $ 500,000      
Future lease payments     $ 37,900,000     $ 54,879,000 $ 1,900,000  
Gross fixed payments     54,600,000          
Lease incentives receivable     16,700,000         $ 16,700,000
Lease liability     $ 14,100,000     $ 37,797,000 $ 1,800,000  
Weighted-average incremental borrowing rate 11.40%   11.40%     11.60% 7.90%  
Renewal term               3 years
Lessee, Operating Lease, Lease Not yet Commenced, Existence of Option to Extend [true false] true              
Lease not yet commenced, renewal term 2 years              
ACELYRIN                
Lessee, Lease, Description [Line Items]                
Lease space | ft²   22,365 10,012          
Term of lease   60 months 65 months          
Renewal term   5 years 3 years          
Monthly rent payments   $ 150,000 $ 30,500          
Percentage increase in monthly rent payments   3.50% 3.00%