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Stock-Based Compensation - Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2024
Stock option plans excluding the 2024 POP      
Options Outstanding      
Options outstanding at beginning of the period (shares) 7,670,908    
Stock options assumed in connection with the ACELYRIN Merger (shares) 4,712,186    
Granted (shares) 6,983,120    
Forfeited or expired (shares) (956,679)    
Options outstanding, vested and expected to vest at end of the period (shares) 18,409,535   7,670,908
Exercisable at end of the period (shares) 10,661,758    
Weighted- Average Exercise Price Per Share      
Weighted-average exercise price, Outstanding at beginning of the period ($ per shares) $ 9.59    
Weighted-average exercise price, Stock options assumed in connection with the ACELYRIN Merger ($ per shares) 12.99    
Weighted-average exercise price, Granted ($ per shares) 4.6    
Weighted-average exercise price, Forfeited or expired ($ per shares) 9.07    
Weighted-average exercise price, Outstanding, vested and expected to vest at end of the period ($ per shares) 8.6   $ 9.59
Exercisable at end of the period ($ per shares) $ 10.66    
Weighted- Average Remaining Contractual Term      
Weighted-average remaining contractual term, Outstanding, vested and expected to vest (in years) 7 years   8 years 2 months 12 days
Weighted-average remaining contractual term, Exercisable at end of the period (in years) 5 years 2 months 12 days    
Aggregate Intrinsic Value      
Aggregate Intrinsic Value, Outstanding at beginning of the period $ 1,777    
Aggregate Intrinsic Values, Outstanding, vested and expected to vest at the end of period 388   $ 1,777
Aggregate Intrinsic Values, Exercisable at the end of period 116    
Vested, fair value $ 22,100 $ 5,400  
2021 Plan      
Aggregate Intrinsic Value      
Unvested and early exercisable shares 2,304,921    
2024 POP      
Options Outstanding      
Options outstanding at beginning of the period (shares) 1,787,880    
Forfeited or expired (shares) (107,056)    
Options outstanding, vested and expected to vest at end of the period (shares) 1,680,824   1,787,880
Weighted- Average Exercise Price Per Share      
Weighted-average exercise price, Outstanding at beginning of the period ($ per shares) $ 10.19    
Weighted-average exercise price, Forfeited or expired ($ per shares) 10.19    
Weighted-average exercise price, Outstanding, vested and expected to vest at end of the period ($ per shares) $ 10.19   $ 10.19
Weighted- Average Remaining Contractual Term      
Weighted-average remaining contractual term, Outstanding, vested and expected to vest (in years) 8 years 7 months 6 days   9 years 3 months 18 days