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Segment Reporting (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Sep. 30, 2024
Jun. 30, 2024
Mar. 31, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenue:                
Total revenue $ 2,066           $ 22,121  
Internal costs                
Total research and development expense 97,836     $ 87,824     303,213 $ 178,350
General and administrative expenses 19,522     10,575     76,267 23,782
Total operating expenses 117,358     98,399     379,480 202,132
Loss from operations (115,292)     (98,399)     (357,359) (202,132)
Total other income (expense), net 4,540     5,282     198,404 2,658
Net loss before income taxes (110,752)     (93,117)     (158,955) (199,474)
Income tax benefit 0     0     8,561 0
Net loss (110,752) $ 59,321 $ (98,963) (93,117) $ (56,508) $ (49,849) (150,394) (199,474)
License revenue                
Revenue:                
Total revenue             17,389  
Collaboration revenue                
Revenue:                
Total revenue 2,066           4,732  
Single reportable segment                
Revenue:                
Total revenue 2,066           22,121  
External costs                
Milestones related to previously acquired IPR&D assets       23,000       23,000
CROs, CMOs and clinical trials 56,457     39,491     187,618 90,604
Professional consulting services 8,227     4,497     22,047 12,787
Other research and development costs 1,617     2,899     6,908 8,493
Internal costs                
Personnel-related costs 24,854     13,476     69,334 32,705
Facilities and overhead costs 6,681     4,461     17,306 10,761
Total research and development expense 97,836     87,824     303,213 178,350
General and administrative expenses 19,522     10,575     76,267 23,782
Total operating expenses 117,358     98,399     379,480 202,132
Loss from operations (115,292)     (98,399)     (357,359) (202,132)
Total other income (expense), net 4,540     5,282     198,404 2,658
Net loss before income taxes (110,752)     (93,117)     (158,955) (199,474)
Income tax benefit             8,561  
Net loss (110,752)     $ (93,117)     (150,394) $ (199,474)
Single reportable segment | License revenue                
Revenue:                
Total revenue             17,389  
Single reportable segment | Collaboration revenue                
Revenue:                
Total revenue $ 2,066           $ 4,732