    <SEC-DOCUMENT>0001104659-25-013980-index.html : 20250327
    <SEC-HEADER>0001104659-25-013980.hdr.sgml : 20250327
    <ACCEPTANCE-DATETIME>20250214152432
    <PRIVATE-TO-PUBLIC>
    ACCESSION NUMBER:		0001104659-25-013980
    CONFORMED SUBMISSION TYPE:	DRS
    PUBLIC DOCUMENT COUNT:		6
    FILED AS OF DATE:		20250214
    <PUBLIC-REL-DATE>20250327
    DATE AS OF CHANGE:		20250214

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ALUMIS INC.
    		CENTRAL INDEX KEY:			0001847367
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DRS
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	377-07730
    		FILM NUMBER:		25627477

    	BUSINESS ADDRESS:
    		STREET 1:		280 EAST GRAND AVENUE
    		CITY:			SOUTH SAN FRANCISCO
    		STATE:			CA
    		ZIP:			94080
    		BUSINESS PHONE:		650-231-6625

    	MAIL ADDRESS:
    		STREET 1:		280 EAST GRAND AVENUE
    		CITY:			SOUTH SAN FRANCISCO
    		STATE:			CA
    		ZIP:			94080

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ESKER THERAPEUTICS, INC.
    		DATE OF NAME CHANGE:	20230427

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	FL2021-001, Inc.
    		DATE OF NAME CHANGE:	20210222
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DRS
    <SEQUENCE>1
    <FILENAME>filename1.htm
    <TEXT>
    Document 1 - file: filename1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>ht_morganstanley-bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: ht_morganstanley-bw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>lg_acelyrin-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: lg_acelyrin-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>lg_alumis-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: lg_alumis-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>lg_guggenheim-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: lg_guggenheim-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>tb_pipeline-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: tb_pipeline-4c.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>