<SEC-DOCUMENT>0001104659-25-013980-index.html : 20250327
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<ACCEPTANCE-DATETIME>20250214152432
<PRIVATE-TO-PUBLIC>
ACCESSION NUMBER:		0001104659-25-013980
CONFORMED SUBMISSION TYPE:	DRS
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20250214
<PUBLIC-REL-DATE>20250327
DATE AS OF CHANGE:		20250214

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALUMIS INC.
		CENTRAL INDEX KEY:			0001847367
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DRS
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	377-07730
		FILM NUMBER:		25627477

	BUSINESS ADDRESS:	
		STREET 1:		280 EAST GRAND AVENUE
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		650-231-6625

	MAIL ADDRESS:	
		STREET 1:		280 EAST GRAND AVENUE
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ESKER THERAPEUTICS, INC.
		DATE OF NAME CHANGE:	20230427

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	FL2021-001, Inc.
		DATE OF NAME CHANGE:	20210222
</SEC-HEADER>
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<TYPE>DRS
<SEQUENCE>1
<FILENAME>filename1.htm
<TEXT>
Document 1 - file: filename1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>ht_morganstanley-bw.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: ht_morganstanley-bw.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>lg_acelyrin-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: lg_acelyrin-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>lg_alumis-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: lg_alumis-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>lg_guggenheim-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: lg_guggenheim-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tb_pipeline-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: tb_pipeline-4c.jpg

</DOCUMENT>
</SEC-DOCUMENT>