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Income Taxes (Details) (USD $) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2012 | Sep. 30, 2012 | Jun. 30, 2012 | Mar. 31, 2012 | Dec. 31, 2011 | Sep. 30, 2011 | Jun. 30, 2011 | Mar. 31, 2011 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Components of Income Tax Expense (Benefit), Continuing Operations [Abstract] |  |  |  |  |  |  |  |  |  |  |
Federal income tax (benefit) provision |  |  |  |  |  |  |  |  | $ (74,000) | $ 15,000 | $ 27,000
Total | 0 | (74,000) | 0 | 0 | 0 | 0 | 0 | 15,000 | (74,000) | 15,000 | 27,000
Significant components of net deferred tax assets [Abstract] |  |  |  |  |  |  |  |  |  |  |
Capitalized research and development expenses | 51,500,000 |  |  |  | 68,700,000 |  |  |  | 51,500,000 | 68,700,000 |
Net operating loss carryforwards | 150,800,000 |  |  |  | 135,700,000 |  |  |  | 150,800,000 | 135,700,000 |
Research and development and other credit carryforwards | 8,500,000 |  |  |  | 21,600,000 |  |  |  | 8,500,000 | 21,600,000 |
Other | 23,300,000 |  |  |  | 14,100,000 |  |  |  | 23,300,000 | 14,100,000 |
Total deferred tax assets | 234,100,000 |  |  |  | 240,100,000 |  |  |  | 234,100,000 | 240,100,000 |
Valuation allowance | (234,100,000) |  |  |  | (240,100,000) |  |  |  | (234,100,000) | (240,100,000) |
Net deferred tax assets | 0 |  |  |  | 0 |  |  |  | 0 | 0 |
Increase (decrease) in the valuation allowance |  |  |  |  |  |  |  |  | (6,000,000) | 25,800,000 | 24,400,000
Unrecognized Tax Benefits [Roll Forward] |  |  |  |  |  |  |  |  |  |  |
Beginning Balance |  |  |  | 0 |  |  |  |  | 0 |  |
Increase related to current year tax position |  |  |  |  |  |  |  |  | 49,000 |  |
Increase related to prior year tax position |  |  |  |  |  |  |  |  | 4,054,000 |  |
Ending Balance | 4,103,000 |  |  |  | 0 |  |  |  | 4,103,000 | 0 |
Unrecognized Tax Benefits that Would Impact Effective Tax Rate | 3,000,000 |  |  |  |  |  |  |  | 3,000,000 |  |
Stock Option [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 500,000 |  |  |  |  |  |  |  | 500,000 |  |
State [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 134,900,000 |  |  |  |  |  |  |  | 134,900,000 |  |
Foreign [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 772,300,000 |  |  |  |  |  |  |  | 772,300,000 |  |
Net operating loss carry-forward expired |  |  |  |  |  |  |  |  | 0 | 0 | 0
California [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net operating loss carry-forward expired |  |  |  |  |  |  |  |  | 10,400,000 | 9,500,000 | 300,000
Federal [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 137,100,000 |  |  |  |  |  |  |  | 137,100,000 |  |
Net operating loss carry-forward expired |  |  |  |  |  |  |  |  | $ 0 | $ 0 | $ 0

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