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Income Taxes (Details) (USD $) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2013 | Sep. 30, 2013 | Jun. 30, 2013 | Mar. 31, 2013 | Dec. 31, 2012 | Sep. 30, 2012 | Jun. 30, 2012 | Mar. 31, 2012 | Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011
Components of Income Tax Expense (Benefit), Continuing Operations [Abstract] |  |  |  |  |  |  |  |  |  |  |
Federal income tax (benefit) provision |  |  |  |  |  |  |  |  | $ (14,000) | $ (74,000) | $ 15,000
Total | 1,000 | (15,000) | 0 | 0 | 0 | (74,000) | 0 | 0 | (14,000) | (74,000) | 15,000
Significant components of net deferred tax assets [Abstract] |  |  |  |  |  |  |  |  |  |  |
Capitalized research and development expenses | 49,400,000 |  |  |  | 51,500,000 |  |  |  | 49,400,000 | 51,500,000 |
Net operating loss carryforwards | 78,400,000 |  |  |  | 150,800,000 |  |  |  | 78,400,000 | 150,800,000 |
Research and development and other credit carryforwards | 8,800,000 |  |  |  | 8,500,000 |  |  |  | 8,800,000 | 8,500,000 |
Other | 23,500,000 |  |  |  | 23,300,000 |  |  |  | 23,500,000 | 23,300,000 |
Total deferred tax assets | 160,100,000 |  |  |  | 234,100,000 |  |  |  | 160,100,000 | 234,100,000 |
Valuation allowance | (160,100,000) |  |  |  | (234,100,000) |  |  |  | (160,100,000) | (234,100,000) |
Net deferred tax assets | 0 |  |  |  | 0 |  |  |  | 0 | 0 |
Increase (decrease) in the valuation allowance |  |  |  |  |  |  |  |  | (74,000,000) | (6,000,000) | 25,800,000
Unrecognized Tax Benefits [Roll Forward] |  |  |  |  |  |  |  |  |  |  |
Beginning Balance |  |  |  | 4,104,000 |  |  |  |  | 4,104,000 |  |
Increase related to current year tax position |  |  |  |  |  |  |  |  | 164,000 |  |
Increase related to prior year tax position |  |  |  |  |  |  |  |  | 6,000 |  |
Ending Balance | 4,274,000 |  |  |  | 4,104,000 |  |  |  | 4,274,000 | 4,104,000 |
Unrecognized Tax Benefits that Would Impact Effective Tax Rate | 3,000,000 |  |  |  |  |  |  |  | 3,000,000 |  |
Stock Option [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 2,100,000 |  |  |  |  |  |  |  | 2,100,000 |  |
State [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 164,000,000 |  |  |  |  |  |  |  | 164,000,000 |  |
California [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net operating loss carry-forward expired |  |  |  |  |  |  |  |  | 16,800,000 | 10,400,000 | 9,500,000
Federal [Member] |  |  |  |  |  |  |  |  |  |  |
Operating Loss Carryforwards [Line Items] |  |  |  |  |  |  |  |  |  |  |
Net Operating Loss Carry-forwards | 205,000,000 |  |  |  |  |  |  |  | 205,000,000 |  |
Net operating loss carry-forward expired |  |  |  |  |  |  |  |  | $ 0 | $ 0 | $ 0

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