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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) (USD $) In Thousands, unless otherwise specified | 3 Months Ended
--- | ---
Mar. 31, 2014 | Mar. 31, 2013
Cash flows from operating activities: |  |  |
Net loss | $ (4,687) |  | $ (24,887)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation | 477 |  | 780
Common stock contribution to 401(k) | 870 |  | 828
Stock-based compensation expense | 3,924 |  | 1,619
Accrued interest on interest bearing obligations | (1,764) |  | 1,586
Revaluation of contingent warrant liabilities | (20,002) |  | 12,840
Amortization of debt discount, final payment fee on debt, and debt issuance costs | 674 |  | 603
Unrealized gain on foreign currency exchange | (66) |  | (515)
Unrealized loss on foreign exchange options | 122 |  | 189
Other non-cash adjustments | 1 |  | (4)
Changes in assets and liabilities: |  |  |
Trade and other receivables, net | (530) |  | 1,997
Prepaid expenses and other assets | (923) |  | (802)
Accounts payable and accrued liabilities | (5,721) |  | (7,097)
Deferred revenue | (524) |  | (111)
Other liabilities | (51) |  | (1,554)
Net cash used in operating activities | (28,200) |  | (14,528)
Cash flows from investing activities: |  |  |
Proceeds from maturities of investments | 0 |  | 20,000
Net purchase of property and equipment | (49) |  | (498)
Net cash (used in) provided by investing activities | (49) |  | 19,502
Cash flows from financing activities: |  |  |
Proceeds from issuance of common stock, net of issuance costs | 3,053 |  | 60
Proceeds from the exercise of warrants | 35 |  | 0
Principal payments of debt | (2,792) |  | 0
Net cash provided by financing activities | 296 |  | 60
Net (decrease) increase in cash and cash equivalents | (27,953) |  | 5,034
Cash and cash equivalents at the beginning of the period | 101,659 | [1] | 45,345
Cash and cash equivalents at the end of the period | 73,706 |  | 50,379
Cash paid for: |  |  |
Interest | 2,194 |  | 333
Non-cash investing and financing activities: |  |  |
Reclassification of contingent warrant liability to equity upon exercise of warrants | (2,525) |  | 0
Interest added to principal balances on long-term debt | $ 0 |  | $ 313
[1] | (Note 1) The condensed consolidated balance sheet as of December 31, 2013 has been derived from the audited consolidated financial statements as of that date included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2013.

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- Definition Noncash value related to the reclassification of a contingent warrant liability to equity upon exercise of warrants during the reporting period + References No definition available. + Details
Name: | xoma_ReclassificationOfContingentWarrantLiabilityToEquityExerciseOfWarrants
Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition The increases (decreases) in the market value of warrants whose gains (losses) were included in earnings. + References No definition available. + Details
Name: | xoma_UnrealizedGainLossOnWarrants
Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration