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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) In Thousands, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012
Cash flows from operating activities: |  |  |
Net loss | $ (38,301)us-gaap_NetIncomeLoss | $ (124,058)us-gaap_NetIncomeLoss | $ (71,065)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation | 1,856 us-gaap_Depreciation | 2,575 us-gaap_Depreciation | 4,124 us-gaap_Depreciation
Common stock contribution to 401(k) | 870 us-gaap_NoncashContributionExpense | 828 us-gaap_NoncashContributionExpense | 1,134 us-gaap_NoncashContributionExpense
Stock-based compensation expense | 10,772 us-gaap_ShareBasedCompensation | 5,099 us-gaap_ShareBasedCompensation | 4,284 us-gaap_ShareBasedCompensation
Accrued interest on interest bearing obligations | (1,444)us-gaap_DebtInstrumentIncreaseAccruedInterest | 2,284 us-gaap_DebtInstrumentIncreaseAccruedInterest | 1,186 us-gaap_DebtInstrumentIncreaseAccruedInterest
Revaluation of contingent warrant liabilities | (45,773)xoma_UnrealizedGainLossOnWarrants | 61,039 xoma_UnrealizedGainLossOnWarrants | 9,172 xoma_UnrealizedGainLossOnWarrants
Restructuring charge related to long-lived assets | 0 us-gaap_AssetImpairmentCharges | 0 us-gaap_AssetImpairmentCharges | 2,460 us-gaap_AssetImpairmentCharges
Amortization of debt discount, final payment fee on debt, and debt issuance costs | 2,707 us-gaap_AmortizationOfFinancingCostsAndDiscounts | 2,470 us-gaap_AmortizationOfFinancingCostsAndDiscounts | 1,958 us-gaap_AmortizationOfFinancingCostsAndDiscounts
Loss on sale and retirement of property and equipment | 0 us-gaap_GainLossOnDispositionOfAssets | 281 us-gaap_GainLossOnDispositionOfAssets | 29 us-gaap_GainLossOnDispositionOfAssets
Unrealized loss on foreign currency exchange | (2,280)us-gaap_ForeignCurrencyTransactionGainLossUnrealized | 662 us-gaap_ForeignCurrencyTransactionGainLossUnrealized | 295 us-gaap_ForeignCurrencyTransactionGainLossUnrealized
Unrealized loss on foreign exchange options | 355 us-gaap_UnrealizedGainLossOnDerivatives | 127 us-gaap_UnrealizedGainLossOnDerivatives | 714 us-gaap_UnrealizedGainLossOnDerivatives
Other non-cash adjustments | (9)us-gaap_OtherNoncashIncomeExpense | (20)us-gaap_OtherNoncashIncomeExpense | (11)us-gaap_OtherNoncashIncomeExpense
Changes in assets and liabilities: |  |  |
Trade and other receivables, net | 472 us-gaap_IncreaseDecreaseInReceivables | 4,486 us-gaap_IncreaseDecreaseInReceivables | 4,064 us-gaap_IncreaseDecreaseInReceivables
Prepaid expenses and other assets | (662)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | 481 us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (158)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Accounts payable and accrued liabilities | (3,774)us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities | 2,901 us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities | 4,485 us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
Deferred revenue | (2,983)us-gaap_IncreaseDecreaseInDeferredRevenue | (3,399)us-gaap_IncreaseDecreaseInDeferredRevenue | (3,511)us-gaap_IncreaseDecreaseInDeferredRevenue
Other liabilities | (88)us-gaap_IncreaseDecreaseInOtherOperatingLiabilities | (1,671)us-gaap_IncreaseDecreaseInOtherOperatingLiabilities | 75 us-gaap_IncreaseDecreaseInOtherOperatingLiabilities
Net cash used in operating activities | (78,282)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (45,915)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (40,765)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities: |  |  |
Purchases of investments | 0 us-gaap_PaymentsToAcquireShortTermInvestments | (19,991)us-gaap_PaymentsToAcquireShortTermInvestments | (56,970)us-gaap_PaymentsToAcquireShortTermInvestments
Proceeds from maturities of investments | 20,000 us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments | 40,000 us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments | 17,000 us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments
Purchase of property and equipment | (325)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (1,169)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (2,509)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Proceeds from sale of property and equipment | 0 us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment | 0 us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment | 463 us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment
Net cash provided by (used in) investing activities | 19,675 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | 18,840 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (42,016)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities: |  |  |
Proceeds from issuance of common stock, net of issuance costs | 41,442 us-gaap_ProceedsFromIssuanceOfCommonStock | 84,338 us-gaap_ProceedsFromIssuanceOfCommonStock | 76,498 us-gaap_ProceedsFromIssuanceOfCommonStock
Proceeds from the exercise of warrants | 35 us-gaap_ProceedsFromWarrantExercises | 2,176 us-gaap_ProceedsFromWarrantExercises | 993 us-gaap_ProceedsFromWarrantExercises
Proceeds from issuance of long-term debt, net of issuance costs | 0 us-gaap_ProceedsFromIssuanceOfLongTermDebt | 0 us-gaap_ProceedsFromIssuanceOfLongTermDebt | 4,434 us-gaap_ProceedsFromIssuanceOfLongTermDebt
Principal payments of debt | (5,917)us-gaap_RepaymentsOfLongTermDebt | (3,125)us-gaap_RepaymentsOfLongTermDebt | (2,143)us-gaap_RepaymentsOfLongTermDebt
Net cash provided financing activities | 35,560 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 83,389 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 79,782 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rate changes on cash | (167)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents | 0 us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents | 0 us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents
Net (decrease) increase in cash and cash equivalents | (23,214)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | 56,314 us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | (2,999)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at the beginning of the period | 101,659 us-gaap_CashAndCashEquivalentsAtCarryingValue | 45,345 us-gaap_CashAndCashEquivalentsAtCarryingValue | 48,344 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at the end of the period | 78,445 us-gaap_CashAndCashEquivalentsAtCarryingValue | 101,659 us-gaap_CashAndCashEquivalentsAtCarryingValue | 45,345 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash paid during the year for: |  |  |
Interest | 3,009 us-gaap_InterestPaid | 1,262 us-gaap_InterestPaid | 1,035 us-gaap_InterestPaid
Non-cash investing and financing activities: |  |  |
Issuance of warrants | 10,258 xoma_IssuanceOfWarrantLiabilities | 0 xoma_IssuanceOfWarrantLiabilities | 6,390 xoma_IssuanceOfWarrantLiabilities
Reclassification of contingent warrant liability to equity upon exercise of warrants | (2,526)xoma_ReclassificationOfContingentWarrantLiabilityToEquityExerciseOfWarrants | (6,171)xoma_ReclassificationOfContingentWarrantLiabilityToEquityExerciseOfWarrants | (940)xoma_ReclassificationOfContingentWarrantLiabilityToEquityExerciseOfWarrants
Interest added to principal balances on long-term debt | 313 xoma_InterestAddedPrincipalBalancesLongTermDebt | 935 xoma_InterestAddedPrincipalBalancesLongTermDebt | 1,160 xoma_InterestAddedPrincipalBalancesLongTermDebt
Investment in Symplmed Pharmaceuticals, LLC | 0 us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1 | 171 us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1 | 0 us-gaap_NoncashOrPartNoncashAcquisitionInvestmentsAcquired1
Discount on long-term debt | $ 0 xoma_DiscountOnLongTermDebt | $ 0 xoma_DiscountOnLongTermDebt | $ (55)xoma_DiscountOnLongTermDebt

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