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Long-Term Debt and Other Financings (Tables) | 9 Months Ended
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Sep. 30, 2015
Debt Disclosure [Abstract] |
Aggregate future principal and final fee payments of interest bearing obligations | Aggregate future principal, final payment fees and discounts of the Company’s total interest bearing obligations - long-term as of September 30, 2015, are as follows (in thousands):
Three months ending December 31, 2015 |  | $ | 475 |
Year ended 2016 |  |  | 9,149 |
Year ended 2017 |  |  | 14,852 |
Year ended 2018 |  |  | 18,117 |
Year ended 2019 |  |  | — |
Year ended 2020 |  |  | 15,394 |
|  |  | 57,987 |
Less: Interest, final payment fee, discount and issuance cost |  |  | (9,402 | )
|  |  | 48,585 |
Less: current portion |  |  | (4,123 | )
|  | $ | 44,462 |
Interest expense and amortization of debt issuance costs | Amortization of debt issuance costs and discounts are included in interest expense. Interest expense in the condensed consolidated statements of comprehensive loss for the three and nine months ended September 30, 2015 and 2014, relates to the following debt instruments (in thousands):
|  | Three Months Ended September 30, |  |  | Nine Months Ended September 30, |
|  | 2015 |  |  | 2014 |  |  | 2015 |  |  | 2014 |
Hercules loan |  | $ | 665 |  |  | $ | — |  |  | $ | 1,551 |  |  | $ | — |
Servier loan |  |  | 278 |  |  |  | 583 |  |  |  | 806 |  |  |  | 1,770 |
GECC term loan |  |  | — |  |  |  | 398 |  |  |  | 548 |  |  |  | 1,268 |
Novartis note |  |  | 84 |  |  |  | 79 |  |  |  | 243 |  |  |  | 234 |
Other |  |  | 3 |  |  |  | — |  |  |  | 4 |  |  |  | 23 |
Total interest expense |  | $ | 1,030 |  |  | $ | 1,060 |  |  | $ | 3,152 |  |  | $ | 3,295 |

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- Definition Tabular disclosure of the combined aggregate amount of maturities and sinking fund requirements for all long-term borrowings for each of the five years following the date of the latest balance sheet date presented. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6802200&loc=d3e1835-112601 + Details
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- Definition Tabular disclosure of aggregate amount of interest expense and the amortization of debt issuance costs on all borrowings. + References No definition available. + Details
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