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Collaborative, Licensing and Other Arrangements - Takeda - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Feb. 28, 2009 | Nov. 30, 2006 | Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Recognition of revenue |  |  | $ 49,064 | $ 5,683 | $ 11,028
Takeda [Member] | Sales Milestone [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Future milestone payments, maximum | $ 3,300 | $ 19,000 |  |  |
Takeda [Member] | Development Milestone [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Future milestone payments with each additional future qualifying product candidate development, maximum |  |  | 20,800 |  |
Takeda [Member] | Collaborative Arrangement [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Recognition of revenue |  |  | $ 100 | $ 1,600 | $ 100
Royalty right expiration period | 10 years | 13 years 6 months |  |  |

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- Definition Revenue from multiple-deliverable arrangements that include licensing fees and services revenue. Licensing revenue is consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Services revenue may be derived by providing other, nonspecified, services during the reporting period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1(d),(e)) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 + Details
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- Definition Amount of potential cash payments that the Company could receive from collaborative arrangements for each of the additional future qualifying product candidate developed. + References No definition available. + Details
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