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Stock-based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2016
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] |
Weighted Average Assumptions | Stock Options The stock options generally vest monthly over four years for employees and one year for directors. Stock options held by employees who qualify for retirement age (defined as employees that are a minimum of 55 years of age and the sum of their age plus years of full-time employment with the Company exceeds 70 years) vest on the earlier of scheduled vest date or the date of retirement. The fair value of the stock options granted during the three months ended March 31, 2016 and 2015, was estimated based on the following weighted average assumptions:
|  | Three Months Ended March 31, |
|  | 2016 |  |  | 2015 |
Dividend yield |  |  | 0 | % |  |  | 0 | %
Expected volatility |  |  | 106 | % |  |  | 82 | %
Risk-free interest rate |  |  | 1.27 | % |  |  | 1.34 | %
Expected term |  | 5.6 years |  |  | 5.6 years |
Stock Option Activity | Stock option activity for the three months ended March 31, 2016, was as follows:
|  | Options |  |  | Weighted Average Exercise Price Per Share |  |  | Weighted Average Remaining Contractual Life (in years) |  |  | Aggregate Intrinsic Value (in thousands) |
Outstanding at January 1, 2016 |  |  | 7,690,297 |  |  | $ | 6.33 |  |  |  |  |  |  |  |  |
Granted |  |  | 65,900 |  |  |  | 1.04 |  |  |  |  |  |  |  |  |
Forfeited, expired or cancelled |  |  | (330,940 | ) |  |  | 8.71 |  |  |  |  |  |  |  |  |
Outstanding at March 31, 2016 |  |  | 7,425,257 |  |  | $ | 6.18 |  |  |  | 6.43 |  |  | $ | — |
Vested and expected to vest at March 31, 2016 |  |  | 7,255,365 |  |  | $ | 6.21 |  |  | 6.37 |  |  | $ | — |
Exercisable at March 31, 2016 |  |  | 5,739,469 |  |  | $ | 6.58 |  |  |  | 5.84 |  |  | $ | — |
Unvested RSU Activity | Unvested RSU activity for the three months ended March 31, 2016, is summarized below:
|  |  |  |  |  | Weighted- |
|  | Number of |  |  | Average Grant- |
|  | Shares |  |  | Date Fair Value |
Unvested balance at January 1, 2016 |  |  | 2,125,761 |  |  | $ | 4.07 |
Granted |  |  | 2,290,344 |  |  |  | 0.76 |
Vested |  |  | (1,052,929 | ) |  |  | 3.24 |
Forfeited |  |  | (117,627 | ) |  |  | 3.52 |
Unvested balance at March 31, 2016 |  |  | 3,245,549 |  |  | $ | 2.03 |
Stock-based Compensation expense | The following table shows total stock-based compensation expense for stock options, RSUs and ESPP in the condensed consolidated statements of comprehensive loss (in thousands):
|  | Three Months Ended March 31, |
|  | 2016 |  |  | 2015 |
Research and development |  | $ | 1,137 |  |  | $ | 2,196 |
Selling, general and administrative |  |  | 1,169 |  |  |  | 1,469 |
Total stock-based compensation expense |  | $ | 2,306 |  |  | $ | 3,665 |

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 14 -Section F + Details
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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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