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Long-Term Debt (Tables) | 6 Months Ended
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Jun. 30, 2016
Debt Disclosure [Abstract] |
Aggregate future principal and final fee payments of interest bearing obligations | Aggregate future principal, final payment fees and discounts of the Company’s total interest bearing obligations as of June 30, 2016, are as follows (in thousands):
Six months ending December 31, 2016 |  | $ | 4,635 |
Year ended 2017 |  |  | 14,768 |
Year ended 2018 |  |  | 18,014 |
Year ended 2019 |  |  | — |
Year ended 2020 |  |  | 15,748 |
|  |  | 53,165 |
Less: interest, final payment fee, discount and issuance cost |  |  | (6,641 | )
|  |  | 46,524 |
Less: interest bearing obligations – current |  |  | (12,138 | )
Interest bearing obligations – non-current |  | $ | 34,386 |
Interest expense and amortization of debt issuance costs | Amortization of debt issuance costs and discounts are included in interest expense. Interest expense in the condensed consolidated statements of comprehensive loss relates to the following debt instruments (in thousands):
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2016 |  |  | 2015 |  |  | 2016 |  |  | 2015 |
Hercules term loan |  | $ | 679 |  |  | $ | 652 |  |  | $ | 1,351 |  |  | $ | 886 |
Servier loan |  |  | 225 |  |  |  | 272 |  |  |  | 451 |  |  |  | 527 |
GECC term loan |  |  | — |  |  |  | — |  |  |  | — |  |  |  | 548 |
Novartis note |  |  | 98 |  |  |  | 80 |  |  |  | 195 |  |  |  | 159 |
Other |  |  | 5 |  |  |  | 3 |  |  |  | 12 |  |  |  | 3 |
Total interest expense |  | $ | 1,007 |  |  | $ | 1,007 |  |  | $ | 2,009 |  |  | $ | 2,123 |

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- Definition Tabular disclosure of the combined aggregate amount of maturities and sinking fund requirements for all long-term borrowings for each of the five years following the date of the latest balance sheet date presented. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6802200&loc=d3e1835-112601 + Details
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- Definition Tabular disclosure of aggregate amount of interest expense and the amortization of debt issuance costs on all borrowings. + References No definition available. + Details
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