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Long-Term Debt - Interest Expense and Amortization of Debt Issuance Costs (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2016 | Sep. 30, 2015 | Sep. 30, 2016 | Sep. 30, 2015
Interest expense and amortization of debt issuance costs [Abstract] |  |  |  |
Interest expense | $ 982 | $ 1,030 | $ 2,991 | $ 3,152
Hercules Term Loan [Member] |  |  |  |
Interest expense and amortization of debt issuance costs [Abstract] |  |  |  |
Interest expense | 651 | 665 | 2,001 | 1,551
Servier Loan [Member] |  |  |  |
Interest expense and amortization of debt issuance costs [Abstract] |  |  |  |
Interest expense | 223 | 278 | 674 | 806
GECC Term Loan [Member] |  |  |  |
Interest expense and amortization of debt issuance costs [Abstract] |  |  |  |
Interest expense |  |  |  | 548
Novartis Note [Member] |  |  |  |
Interest expense and amortization of debt issuance costs [Abstract] |  |  |  |
Interest expense | 104 | 84 | 299 | 243
Other [Member] |  |  |  |
Interest expense and amortization of debt issuance costs [Abstract] |  |  |  |
Interest expense | $ 4 | $ 3 | $ 17 | $ 4

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- References No definition available. + Details
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- Definition Amount of the cost of borrowed funds accounted for as interest expense for debt. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.8) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 + Details
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