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Fair Value Measurements - Outstanding Debt Carrying Amount and Estimated Fair Value (Details) - USD ($) $ in Thousands | Sep. 30, 2016 | Dec. 31, 2015
--- | --- | ---
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |
Interest-bearing obligations, Carrying amount | $ 45,219 | $ 48,667
Interest bearing obligations, Estimated Fair value | 45,793 | 49,810
Hercules Term Loan [Member] |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |
Interest-bearing obligations, Carrying amount | 18,465 | 19,653
Interest bearing obligations, Estimated Fair value | 19,421 | 21,231
Novartis Note [Member] |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |
Interest-bearing obligations, Carrying amount | 13,879 | 13,683
Interest bearing obligations, Estimated Fair value | 13,536 | 13,394
Servier Loan [Member] |  |
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] |  |
Interest-bearing obligations, Carrying amount | 12,875 | 15,331
Interest bearing obligations, Estimated Fair value | $ 12,836 | $ 15,185

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- Definition Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-03(a)(16)) -URI http://asc.fasb.org/extlink&oid=6879938&loc=d3e572229-122910 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-03(16)) -URI http://asc.fasb.org/extlink&oid=6876686&loc=d3e534808-122878 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- Definition The fair value amount of long-term debt whether such amount is presented as a separate caption or as a parenthetical disclosure. Additionally, this element may be used in connection with the fair value disclosures required in the footnote disclosures to the financial statements. The element may be used in both the balance sheet and disclosure in the same submission. + References No definition available. + Details
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