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Long-Term Debt (Tables) | 6 Months Ended
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Jun. 30, 2017
Debt Disclosure [Abstract] |
Aggregate Future Principal and Discounts of Interest Bearing Obligations | Payments of Interest Bearing Obligations Aggregate future principal and discounts of the Company’s total interest bearing obligations as of June 30, 2017, are as follows (in thousands):
Six months ending December 31, 2017 |  | $ | 5,832 |
Year ending December 31, 2018 |  |  | 8,068 |
Year ending December 31, 2019 |  |  | — |
Year ending December 31, 2020 |  |  | 16,044 |
|  |  | 29,944 |
Less: interest, discount and issuance cost |  |  | (2,083 | )
|  |  | 27,861 |
Less: interest bearing obligations – current |  |  | (13,539 | )
Interest bearing obligations – non-current |  | $ | 14,322 |
Interest Expense and Amortization of Debt Issuance Costs | Amortization of debt issuance costs and discounts are included in interest expense. Interest expense in the condensed consolidated statements of comprehensive income (loss) relates to the following debt instruments (in thousands):
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2017 |  |  | 2016 |  |  | 2017 |  |  | 2016 |
Hercules term loan |  | $ | — |  |  | $ | 679 |  |  | $ | 311 |  |  | $ | 1,351 |
Servier loan |  |  | 178 |  |  |  | 225 |  |  |  | 355 |  |  |  | 451 |
Novartis note |  |  | 119 |  |  |  | 98 |  |  |  | 236 |  |  |  | 195 |
Other |  |  | — |  |  |  | 5 |  |  |  | 4 |  |  |  | 12 |
Total interest expense |  | $ | 297 |  |  | $ | 1,007 |  |  | $ | 906 |  |  | $ | 2,009 |

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- Definition Tabular disclosure of the combined aggregate amount of maturities and sinking fund requirements for all long-term borrowings for each of the five years following the date of the latest balance sheet date presented. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6802200&loc=d3e1835-112601 + Details
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