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Collaborative, Licensing and Other Arrangements - Sale of Future Revenue Streams - Additional Information (Details) $ in Thousands |  | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Dec. 21, 2016 USD ($) | Jun. 30, 2017 USD ($) | Jun. 30, 2017 USD ($) Agreement | Dec. 31, 2016 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Deferred revenue – current |  | $ 1,425 | $ 1,425 | $ 899 | [1]
Deferred revenue, non-current |  | 17,255 | $ 17,255 | 18,000 | [1]
HCRP [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Number of royalty Interest acquisition agreements | Agreement |  |  | 2 |  |
Deferred revenue |  | 18,000 | $ 18,000 |  |
Contract and other revenue |  | 100 | 200 |  |
Deferred revenue – current |  | 500 | 500 |  |
Deferred revenue, non-current |  | $ 17,300 | $ 17,300 | $ 18,000 |
HCRP [Member] | First Acquisition Agreement [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Upfront cash payment received | $ 6,500 |  |  |  |
Eligible potential additional payments receivable upon achievement of specified net sales milestones in 2017, 2018 and 2019 | 4,000 |  |  |  |
HCRP [Member] | Second Acquisition Agreement [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Upfront cash payment received | $ 11,500 |  |  |  |
[1] | The condensed consolidated balance sheet as of December 31, 2016 has been derived from the audited consolidated financial statements as of that date included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2016.

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