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Collaborative, Licensing and Other Arrangements - Novartis - Additional Information (Details) - Collaborative Arrangement [Member] - Novartis [Member] - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2017 | Jun. 30, 2017 | Dec. 31, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Upfront payment received |  |  | $ 37.0
Eligible milestone payments receivable upon achievement of development, regulatory and commercial milestones |  | $ 480.0 |
Milestone received under the collaboration agreement | $ 10.0 |  |

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- Details
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