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Long-Term Debt and Other Financings (Tables) | 12 Months Ended
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Dec. 31, 2017
Debt Disclosure [Abstract] |
Interest Expense and Amortization of Debt Issuance Costs | Amortization of debt issuance costs and discounts are included in interest expense. Interest expense in the consolidated statements of comprehensive income (loss) for the years ended December 31, 2017, 2016, and 2015, relates to the following debt instruments (in thousands):
|  | Year Ended December 31, |
|  | 2017 |  |  | 2016 |  |  | 2015 |
Novartis note |  | $ | 490 |  |  | $ | 405 |  |  | $ | 329 |
Servier loan |  |  | 431 |  |  |  | 892 |  |  |  | 1,083 |
Hercules loan |  |  | 311 |  |  |  | 2,628 |  |  |  | 2,223 |
Other |  |  | 6 |  |  |  | 21 |  |  |  | 130 |
Total interest expense |  | $ | 1,238 |  |  | $ | 3,946 |  |  | $ | 3,765 |

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- Definition Tabular disclosure of aggregate amount of interest expense and the amortization of debt issuance costs on all borrowings. + References No definition available. + Details
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