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Long-Term Debt and Other Financings - Hercules Term Loan - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Feb. 27, 2015 | Jan. 31, 2017 | Feb. 29, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Debt Instrument [Line Items] |  |  |  |  |  |
Repayment of principal |  |  |  | $ 16,380 | $ 6,890 | $ 6,128
Loss on extinguishment of debt |  |  |  | $ (650) |  | (429)
Aggregate number of unregistered shares of common stock called by warrants (in shares) |  |  | 8,249 |  |  |
Exercise price of warrants (in dollars per share) |  |  | $ 15.40 |  |  |
Fair value of warrants |  |  | $ 100 |  |  |
Exercisable period of warrants |  |  | 5 years |  |  |
Hercules Term Loan [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Maturity date | Sep. 01, 2018 |  |  |  |  |
Variable rate basis |  |  |  | The Hercules Term Loan had a variable interest rate that is the greater of either (i) 9.40% plus the prime rate as reported from time to time in The Wall Street Journal minus 7.25%, or (ii) 9.40%. |  |
Period of principal and interest amortized | 30 months |  |  |  |  |
Amortization of interest payments period end date | Jun. 01, 2016 |  |  |  |  |
Period of interest | 1 month |  |  |  |  |
Additional interest rate in case of default | 5.00% |  |  |  |  |
Debt issuance costs | $ 500 |  |  |  |  |
Final payment fee | $ 1,200 |  |  |  |  |
Amortization of debt discount |  |  |  | $ 200 | 700 | $ 500
Outstanding principal balance |  |  |  |  | 17,500 |
Carrying value of the loan |  |  |  |  | $ 16,900 |
Repayment of principal |  | $ 10,000 |  |  |  |
Prepayment charge not required to pay |  |  |  | 1.00% |  |
Loss on extinguishment of debt |  |  |  | $ 500 |  |
Aggregate number of unregistered shares of common stock called by warrants (in shares) | 9,063 |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ 66.20 |  |  |  |  |
Fair value of warrants | $ 500 |  |  |  |  |
Exercisable period of warrants | 5 years |  |  |  |  |
Warrants expiration period | 2020-02 |  |  |  |  |
Minimum [Member] | Hercules Term Loan [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Percentage bearing variable rate |  |  |  | 9.40% |  |
Prime Rate [Member] | Hercules Term Loan [Member] |  |  |  |  |  |
Debt Instrument [Line Items] |  |  |  |  |  |
Basis spread, addition |  |  |  | 9.40% |  |
Basis spread, subtraction |  |  |  | 7.25% |  |

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