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CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS) - USD ($) shares in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Revenues: |  |  |
License fees | $ 52,311,000 | $ 3,296,000 | $ 49,064,000
Contract and other | 379,000 | 2,268,000 | 6,383,000
Total revenues | 52,690,000 | 5,564,000 | 55,447,000
Operating expenses: |  |  |
Research and development | 7,875,000 | 44,234,000 | 70,852,000
General and administrative | 24,337,000 | 18,322,000 | 20,620,000
Restructuring | 3,447,000 | 4,566,000 | 3,699,000
Total operating expenses | 35,659,000 | 67,122,000 | 95,171,000
Income (loss) from operations | 17,031,000 | (61,558,000) | (39,724,000)
Other income (expense): |  |  |
Interest expense | (1,238,000) | (3,946,000) | (3,765,000)
Loss on extinguishment of debt | (650,000) |  | (429,000)
Other income, net | 1,115,000 | 1,510,000 | 5,500,000
Revaluation of contingent warrant liabilities |  | 10,464,000 | 17,812,000
Income (loss) before income tax | 16,258,000 | (53,530,000) | (20,606,000)
Provision for income taxes | (1,662,000) | 0 | 0
Net income (loss) and comprehensive income (loss) | 14,596,000 | (53,530,000) | (20,606,000)
Net income (loss) and comprehensive income (loss) available to common stockholders, basic | 5,714,000 | (53,530,000) | (20,606,000)
Net income (loss) and comprehensive income (loss) available to common stockholders, diluted | $ 5,810,000 | $ (53,530,000) | $ (20,606,000)
Basic net income (loss) per share available to common stockholders | $ 0.75 | $ (8.89) | $ (3.50)
Diluted net income (loss) per share available to common stockholders | $ 0.73 | $ (8.89) | $ (3.50)
Weighted average shares used in computing basic net income (loss) per share available to common stockholders | 7,619 | 6,021 | 5,890
Weighted average shares used in computing diluted net income (loss) per share available to common stockholders | 7,980 | 6,021 | 5,890

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