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Collaborative, Licensing and Other Arrangements - Servier - Additional Information (Details) - Collaborative Arrangement [Member] - Servier [Member] € in Millions, $ in Millions | 1 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jan. 31, 2011 USD ($) | Jan. 31, 2011 EUR (€) | Mar. 25, 2016 USD ($) | Dec. 31, 2016 USD ($) | Dec. 31, 2015 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Upfront payment received | $ 15.0 |  |  |  |
Proceeds from loan | $ 19.5 | € 15.0 |  |  |
Deferred revenue recognized |  |  | $ 0.6 |  |
Contract and other revenue |  |  |  | $ 0.6 | $ 1.2

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- Definition Cash received from principal payments made on loans related to operating activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3536-108585 + Details
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- Details
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