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Collaborative, Licensing and Other Arrangements - Novo Nordisk - Additional Information (Details) - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2017 | Dec. 31, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |
Performance deliverable period for license and transfer of technology and knowhow | 60 days |
Upfront payment recognized as revenue |  | $ 5.0
Collaborative Arrangement [Member] | Novo Nordisk [Member] |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |
Upfront payment received |  | $ 5.0
Eligible milestone payments receivable upon achievement of development, regulatory and commercial milestones | $ 290.0 |

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- Details
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