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Dispositions - Additional Information (Details) - USD ($) |  |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Dec. 31, 2015 | Nov. 05, 2015 | Nov. 04, 2015 | Feb. 28, 2017 | Dec. 31, 2017 | Dec. 31, 2015
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Gain on sale of business |  |  |  |  |  | $ 3,505,000
Asset Purchase Agreement and Ology Bioservices License Agreement [Member] |  |  |  |  |  |
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Cash payments from Ology Bioservices |  |  |  | $ 4,500,000 |  |
Number of shares removed from obligation to issue of common stock |  |  |  | 23,008 |  |
Contingent upon achieving certain specified future operating objectives |  |  |  | $ 3,000,000 |  |
Amount entitled to receive |  |  |  |  | $ 4,600,000 |
Amount received from sale of discontinued operation |  |  |  |  | 2,200,000 |
Remaining consideration amount receivable |  |  |  |  | 2,400,000 |
Remaining amount receivable in monthly installments |  |  |  |  | 1,700,000 |
Remaining amount receivable in quarterly installments |  |  |  |  | $ 700,000 |
Biodefense Business [Member] |  |  |  |  |  |
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Sales of business, number of common stock shares eligible to receive |  |  | 23,008 |  |  |
Royalties receivable percentage on net sales |  |  | 15.00% |  |  |
Biodefense Business [Member] | Maximum [Member] |  |  |  |  |  |
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Cash payments from Ology Bioservices |  |  | $ 4,500,000 |  |  |
Manufacturing Facility in Berkeley, California [Member] | Agenus Purchase Agreement [Member] |  |  |  |  |  |
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Cash received from sale of business | $ 4,700,000 |  |  |  |  |
Sale of business, value of common stock shares received | 500,000 |  |  |  |  | 500,000
Liabilities assumed | $ 300,000 |  |  |  |  |
Sales of business, number of common stock shares received | 109,211 |  |  |  |  |
Contingent consideration value of common stock to be received |  |  |  |  |  | 500,000
Consideration received for employees who would not have otherwise been retained |  |  |  |  |  | 200,000
Carrying value of business sold | $ 2,200,000 |  |  |  |  | 2,200,000
Manufacturing Facility in Berkeley, California [Member] | Agenus Purchase Agreement [Member] | Other Income (Expense), Net [Member] |  |  |  |  |  |
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Gain on sale of business |  |  |  |  |  | $ 3,500,000
Manufacturing Facility in Berkeley, California [Member] | Maximum [Member] | Agenus Purchase Agreement [Member] |  |  |  |  |  |
Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] |  |  |  |  |  |
Cash received from sale of business |  | $ 5,000,000 |  |  |  |
Sale of business, value of common stock shares received |  | $ 1,000,000 |  |  |  |

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