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Commitments and Contingencies - Additional Information (Details) |  |  |  | 3 Months Ended | 6 Months Ended
--- | --- | --- | --- | --- | ---
Jun. 30, 2018 USD ($) RenewalOption | Apr. 14, 2018 USD ($) Facility | Nov. 21, 2017 USD ($) Facility | Jun. 30, 2018 USD ($) RenewalOption | Jun. 30, 2018 USD ($) RenewalOption
Commitments And Contingencies [Line Items] |  |  |  |  |
Estimate of milestone payments | $ 15,500,000 |  |  | $ 15,500,000 | $ 15,500,000
Operating leases, expiry date |  |  |  |  | 2023-04
Operating leases, number of successive renewal options | RenewalOption | 2 |  |  | 2 | 2
Operating leases, extended lease term | 5 years |  |  | 5 years | 5 years
Operating leases, number of portions of leased facilities | Facility |  | 1 | 1 |  |
Operating leases, number of leased facilities | Facility |  | 3 | 3 |  |
Operating leases, sublease commencement date |  | May 01, 2018 | Dec. 26, 2017 |  |
Operating leases sublease income receivable |  | $ 1,100,000 | $ 5,100,000 |  |
Operating leases sublease expiry date |  | 2023-04 | 2023-04 |  |
Sublease tenant improvement allowance |  | $ 65,000 | $ 800,000 |  |
Sublease loss |  |  | 800,000 |  |
Sublease income |  |  |  | $ 400,000 | $ 700,000
Sublease broker commissions |  | $ 89,000 |  |  |
Restructuring Charges [Member] |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Sublease loss |  |  |  | 600,000 | 600,000
Sublease Agreement Commenced on May 1,2018 [Member] |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Sublease income |  |  |  | $ 100,000 | $ 100,000
Standby Letter of Credit [Member] |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |
Letter of credit amount |  |  | $ 1,000,000 |  |
Funds drawn from letter of credit | $ 0 |  |  |  |

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- Definition Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 3 -Subparagraph (a)(3) -URI http://asc.fasb.org/extlink&oid=77888426&loc=SL77918673-209980 + Details
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