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Licensing and Other Arrangements - Sale of Future Revenue Streams - Additional Information (Details) $ in Thousands |  | 12 Months Ended
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Dec. 21, 2016 USD ($) | Dec. 31, 2018 USD ($) Agreement | Dec. 31, 2017 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Unearned revenue recognized under units-of-revenue method |  | $ 490 | $ 615
Unearned revenue recognized under units-of-revenue method – long-term |  | $ 17,017 | 17,123
HCRP [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Number of royalty Interest acquisition agreements | Agreement |  | 2 |
Unearned revenue recognized under units-of-revenue method |  | $ 18,000 |
Revenue recognized under units-of-revenue method |  | 200 | 300
Unearned revenue recognized under units-of-revenue method |  | 500 | 600
Unearned revenue recognized under units-of-revenue method – long-term |  | 17,000 | $ 17,100
HCRP [Member] | First Acquisition Agreement [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Upfront cash payment received | $ 6,500 |  |
Eligible potential additional payments receivable upon achievement of specified net sales milestones in future years | 4,000 | $ 2,000 |
HCRP [Member] | Second Acquisition Agreement [Member] |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Upfront cash payment received | $ 11,500 |  |

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