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Commitments and Contingencies | 12 Months Ended
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Dec. 31, 2018
Commitments And Contingencies Disclosure [Abstract] |
Commitments and Contingencies | 14. Commitments and Contingencies Collaborative Agreements, Royalties and Milestone Payments The Company has committed to make potential future milestone payments to third parties as part of licensing and development programs. Payments under these agreements become due and payable only upon the achievement of certain developmental, regulatory and commercial milestones by the Company’s licensees. Because it is uncertain if and when these milestones will be achieved, such contingencies, aggregating up to $7.5 million (assuming one product per contract meets all milestones events) have not been recorded on the accompanying consolidated balance sheets. The Company is unable to determine precisely when and if payment obligations under the agreements will become due as these obligations are based on milestone events, the achievement of which is subject to a significant number of risks and uncertainties. Operating Leases The Company leases two facilities in Berkeley, California and office equipment under operating leases expiring on various dates through April 2023. These leases require the Company to pay taxes, insurance, maintenance and minimum lease payments. In September 2017, the Company entered into a third lease agreement for an office facility in Emeryville, California. The lease has a term of 63 months and commenced on November 14, 2017. Under the lease agreement the Company will make total lease payments of $0.8 million through February 2023. Total rental expense, including other costs required under the Company’s leases, was approximately $2.1 million and $2.4 million for the years ended December 31, 2018 and 2017, respectively. Rental expense based on leases allowing for escalated rent payments are recognized on a straight-line basis. At the expiration of the lease, the Company is required to restore certain of its leased property to certain conditions in place at the time of lease inception. On November 21, 2017, the Company entered into a non-cancellable sublease agreement for a portion of one of its three leased facilities. The term of the sublease agreement commenced on December 26, 2017. Under the term of the sublease agreement, the Company will receive $5.1 million in base lease payments plus reimbursement of certain operating expenses over the term of the sublease, which ends at the same time as the original lease in April 2023. Under the sublease agreement, the Company’s future sublease income will be equal to the amount required to be paid to the Company’s landlord. In addition, the sublease provides for a tenant improvement allowance of $0.8 million to the subtenant, which was funded by the Company in January 2018. Upon execution of the sublease agreement, the Company recognized a loss on the sublease equal to the tenant improvement allowance. Under the sublease agreement, the sub-lessee executed a standby letter of credit naming the Company as the beneficiary amounting to $1.0 million as security under the sublease in the event of uncured default by the sub-lessee. As of December 31, 2018, the Company has not drawn any funds from the letter of credit as there was no default by the sub-lessee. During the year ended December 31, 2018, the Company recognized $1.5 million of sublease income under this agreement. On April 14, 2018, the Company entered into a non-cancellable sublease agreement for a portion of one of its three leased facilities. The term of the sublease agreement commenced on May 1, 2018. Under the term of the sublease agreement, the Company will receive $1.1 million in base lease payments plus reimbursement of certain operating expenses over the term of the sublease, which ends at the same time as the original lease in April 2023. Under the sublease agreement, the Company’s future sublease income is less than the amount required to be paid to the Company’s landlord. In addition, the sublease provides for a tenant improvement allowance of $65,000 to the subtenant, and payment of broker commissions of $89,000. Upon execution of the sublease agreement, the Company recognized a loss on the sublease of $0.6 million, which was recorded in the restructuring charges line item of the consolidated statements of operations and comprehensive loss. During the year ended December 31, 2018, the Company recognized $0.3 million of sublease income under this agreement. In October 2018, the Company entered into a non-cancellable sublease agreement for a portion of one of its three leased facilities. The term of the sublease agreement commenced on October 24, 2018. Under the term of the sublease agreement, the Company will receive $1.7 million in base lease payments over the term of the sublease, which ends at the same time as the original lease in May 2021. Under the sublease agreement, the Company’s future sublease income is less than the amount required to be paid to the Company’s landlord. In addition, the sublease provides for payment of broker commissions of $137,000. As the sublease agreement was executed after the Company met the criteria of a cease-use date for the leased faciality, the Company did not recognize a loss on the sublease. Instead, the Company remeasured the lease-related restructuring liability based on actual sublease income from the sublease agreement (see Note 8) and the resulting adjustment was recorded in the restructuring charges line item of the consolidated statements of operations and comprehensive loss. The Company estimates future minimum lease amounts (in thousands):
Year Ending December 31, |  | Rent Payments |  |  | Sublease income(1) |
2019 |  |  | 4,381 |  |  |  | 2,249 |
2020 |  |  | 3,923 |  |  |  | 2,376 |
2021 |  |  | 3,156 |  |  |  | 2,006 |
2022 |  |  | 2,611 |  |  |  | 1,746 |
2023 |  |  | 854 |  |  |  | 592 |
Thereafter |  |  | — |  |  |  | — |
Total minimum lease payments |  | $ | 14,925 |  |  | $ | 8,969 |
| (1) | Sublease income includes base lease payments and expected reimbursement of certain operating expenses under executed sublease agreements as of December 31, 2018.

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- Definition The entire disclosure for commitments and contingencies. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 450 -URI http://asc.fasb.org/topic&trid=2127136 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 440 -URI http://asc.fasb.org/topic&trid=2144648 + Details
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