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Licensing and Other Arrangements - NIAID - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 30, 2008 | Dec. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Deferred revenue balance classified as contract liability due to government adjustment |  | $ 798 | $ 798 |
National Institute of Allergy and Infectious Diseases "NIAID" [Member] |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Contract liabilities |  | 800 | $ 800 |
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 2 [Member] |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Total contract amount awarded | $ 64,800 |  |  |
Contracts revenue wrote off |  | $ 400 |  |
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 3 [Member] |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Contractual term | 3 years |  |  |
Accounts receivable |  |  |  | $ 400
Deferred revenue balance classified as contract liability due to government adjustment |  |  |  | $ 800

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