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Licensing and Other Arrangements - Novartis - Additional Information (Details) $ / shares in Units, € in Millions |  |  | 3 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Aug. 24, 2017 USD ($) Agreement Obligation $ / shares shares | Aug. 24, 2017 EUR (€) Agreement Obligation shares | Sep. 30, 2015 | Jun. 30, 2017 USD ($) | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Dec. 31, 2015 USD ($)
Novartis Pharma AG [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Upfront payment received | $ 25,700,000 |  |  |  |  |  |
Common stock aggregate fair value | 4,800,000 |  |  |  |  |  |
Common stock premium | $ 200,000 |  |  |  |  |  |
Number of license agreements | Agreement | 2 | 2 |  |  |  |  |
Number of performance obligations | Obligation | 2 | 2 |  |  |  |  |
Remaining performance obligations | $ 0 |  |  |  |  |  |
License agreement transaction price | 40,200,000 |  |  |  |  |  |
Contract liabilities |  |  |  |  | $ 0 | $ 0 |
Contract assets |  |  |  |  | 0 | 0 |
Revenue recognize |  |  |  |  | 0 | 0 |
Capitalized contract costs |  |  |  |  | 0 | 0 |
Novartis Pharma AG [Member] | Licenses and Related Materials, Process and Know-How and Filings to Regulatory Authority [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Recognized the entire transaction price as revenue upon completion of delivery |  |  |  |  |  | 40,200,000 |
Novartis Pharma AG [Member] | Common Stock [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Cash received from sale of shares | $ 5,000,000 |  |  |  |  |  |
Number of shares sold | shares | 539,131 | 539,131 |  |  |  |  |
Sale of stock price per share | $ / shares | $ 9.2742 |  |  |  |  |  |
Common stock closing price | $ / shares | $ 8.93 |  |  |  |  |  |
Novartis Pharma AG [Member] | Les Laboratories Servier [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Repayments of debt | $ 14,300,000 | € 12.0 |  |  |  |  |
Novartis Pharma AG [Member] | XOMA-052 License Agreement [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
License agreement consideration received | 30,000,000 |  |  |  |  |  |
Upfront payment received | 15,700,000 |  |  |  |  |  |
Eligible milestone payments receivable upon achievement of development, regulatory and commercial milestones | $ 438,000,000 |  |  |  |  |  |
Agreement termination prior written notice period | 6 months | 6 months |  |  |  |  |
Novartis Pharma AG [Member] | IL-1 Target License Agreement [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Upfront payment received | $ 10,000,000 |  |  |  |  |  |
Novartis International [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Cash received from sale of shares | $ 5,000,000 |  |  |  |  |  |
Number of shares sold | shares | 539,131 | 539,131 |  |  |  |  |
Common stock aggregate fair value | $ 4,800,000 |  |  |  |  |  |
Common stock closing price | $ / shares | $ 8.93 |  |  |  |  |  |
Common stock premium | $ 200,000 |  |  |  |  |  |
Novartis International [Member] | License Agreement [Member] |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Eligible milestone payments receivable upon achievement of development, regulatory and commercial milestones |  |  |  |  | 470,000,000 |  |
Contract liabilities |  |  |  |  | 0 | 0 |
Contract assets |  |  |  |  | 0 | 0 |
Capitalized contract costs |  |  |  |  | $ 0 | 0 |
Agreement termination notice period |  |  | 180 days |  |  |  |
Upfront payment recognized as revenue |  |  |  |  |  |  | $ 37,000,000
Milestone received under the collaboration agreement |  |  |  | $ 10,000,000 |  | $ 10,000,000 |

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