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Licensing and Other Arrangements - NIAID - Additional Information (Details) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | ---
Mar. 31, 2019 | Dec. 31, 2017 | Dec. 31, 2018 | Dec. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Deferred revenue balance classified as contract liability due to government adjustment | $ 798 |  | $ 798 | [1] |
National Institute of Allergy and Infectious Diseases "NIAID" [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Contract liabilities | 800 |  | $ 800 |  |
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 2 [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Total contract amount awarded | $ 64,800 |  |  |  |
Contracts revenue wrote off |  | $ 400 |  |  |
National Institute of Allergy and Infectious Diseases "NIAID" [Member] | Arrangement with Governmental Agency 3 [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Contractual term | 3 years |  |  |  |
Accounts receivable |  |  |  |  | $ 400
Deferred revenue balance classified as contract liability due to government adjustment |  |  |  |  | $ 800
[1] | The condensed consolidated balance sheet as of December 31, 2018 has been derived from the audited consolidated financial statements as of that date included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2018.

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