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Licensing and Other Arrangements - Sale of Future Revenue Streams - Additional Information (Details) $ in Thousands |  | 3 Months Ended | 9 Months Ended |
--- | --- | --- | --- | ---
Dec. 21, 2016 USD ($) | Sep. 30, 2019 USD ($) | Sep. 30, 2018 USD ($) | Jun. 30, 2018 USD ($) | Sep. 30, 2019 USD ($) Agreement | Sep. 30, 2018 USD ($) | Dec. 31, 2018 USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Unearned revenue recognized under units-of-revenue method, long-term |  | $ 15,876 |  |  | $ 15,876 |  | $ 17,017 | [1]
HCRP [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Number of royalty Interest acquisition agreements | Agreement |  |  |  |  | 2 |  |  |
Unearned revenue recognized under units-of-revenue method |  | 18,000 |  |  | $ 18,000 |  |  |
Revenue recognized under units-of-revenue method |  | 300 | $ 100 |  | 800 | $ 100 |  |
Reversed revenue recognized under units-of-revenue method |  |  |  | $ 100 |  |  |  |
Decrease in net revenue due to change in estimate of product sales |  |  |  |  |  | $ 100 |  |
Unearned revenue recognized under units-of-revenue method |  | 900 |  |  | 900 |  | 500 |
Unearned revenue recognized under units-of-revenue method, long-term |  | $ 15,900 |  |  | 15,900 |  | $ 17,000 |
HCRP [Member] | First Acquisition Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront cash payment received | $ 6,500 |  |  |  |  |  |  |
Eligible potential additional payments receivable upon achievement of specified net sales milestones in future years | 4,000 |  |  |  | $ 2,000 |  |  |
HCRP [Member] | Second Acquisition Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront cash payment received | $ 11,500 |  |  |  |  |  |  |
[1] | The consolidated balance sheet as of December 31, 2018 has been derived from the audited consolidated financial statements as of that date included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2018.

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