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Royalty Purchase Agreements - Kuros (Details) - USD ($) $ in Thousands |  | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jul. 14, 2021 | Sep. 30, 2021 | Dec. 31, 2020
Agreements |  |  |
Long-term royalty receivables |  | $ 55,075 | $ 34,575
Impairment of long-term royalty receivable |  | 0 | $ 0
Kuros | Royalty Purchase Agreement [Member] |  |  |
Agreements |  |  |
Royalties entity has right to receive (as a percent) | 100.00% |  |
Pre-commercial milestone payments | $ 25,500 |  |
Upfront payment | 7,000 |  |
Potential future sales milestone payments | 142,500 |  |
Long-term royalty receivables | $ 7,000 |  |
Impairment of long-term royalty receivable |  | $ 0 |

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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- Definition Maximum eligible milestone payments receivable upon achievement of development, pre-commercial milestones. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
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Period Type: | duration

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- Definition Maximum eligible milestone payments receivable upon achievement of sales milestones. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
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- Definition The aggregate amount of write-downs for impairments recognized during the period for long term royalty receivable assets. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Definition Long-term royalty receivable non current. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Royalties entity has the right to receive as a percentage. + References No definition available. + Details
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Namespace Prefix: | xoma_
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Balance Type: | na
Period Type: | duration

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- Definition The cash outflow for initial payment under agreement. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

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- Details
Name: | srt_CounterpartyNameAxis=xoma_KurosBiosciencesAgKurosUsLlcAndKurosRoyaltyFundUsLlcMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
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Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |