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Royalty and Commercial Payment Purchase Agreements - Summary (Details) - USD ($) $ in Thousands | 3 Months Ended |
--- | --- | ---
Mar. 31, 2022 | Dec. 31, 2021
Agreements |  |
Long-term royalty and commercial payment receivables | $ 69,075 | $ 69,075
Acquisition of royalty and commercial payment rights | 0 |
Cash receipts for achievement of contractual milestones | $ 0 |

X
- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Cash receipts for achievement of contractual milestones. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Definition Long-term royalty and commercial rights receivables, non current. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

X
- Definition Royalty and commercial payment rights acquired. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration