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Licensing and Other Arrangements - Novartis - VPM087 and IL-1 Beta (Details) $ / shares in Units, $ in Thousands, € in Millions |  | 3 Months Ended |
--- | --- | --- | ---
Aug. 24, 2017 USD ($) item agreement $ / shares shares | Aug. 24, 2017 EUR (€) item agreement shares | Mar. 31, 2022 USD ($) | Mar. 31, 2021 USD ($) | Dec. 31, 2021 USD ($)
Licensing and other arrangements |  |  |  |  |
Revenue from contracts with customers |  |  | $ 2,750 | $ 19 |
Novartis Pharma AG [Member] | Gevokizumab License Agreement and IL-1 Target License Agreement |  |  |  |  |
Licensing and other arrangements |  |  |  |  |
Transaction price | $ 40,200 |  |  |  |
Cash payment received | 25,700 |  |  |  |
License agreement consideration received, repayment of debt | 14,300 |  |  |  |
Common stock premium | $ 200 |  |  |  |
Number of license agreements | agreement | 2 | 2 |  |  |
Number of arrangements | item | 1 | 1 |  |  |
Number of performance obligations | item | 2 | 2 |  |  |
Remaining performance obligations |  |  | 0 |  |
Revenue from contracts with customers |  |  | 0 | $ 0 |
Contract assets |  |  | 0 |  | $ 0
Contract liabilities |  |  | 0 |  | 0
Capitalized contract costs |  |  | $ 0 |  | $ 0
Novartis Pharma AG [Member] | Gevokizumab License Agreement |  |  |  |  |
Licensing and other arrangements |  |  |  |  |
License agreement consideration received | $ 30,000 |  |  |  |
Cash payment received | 15,700 |  |  |  |
License agreement consideration received, repayment of debt | 14,300 | € 12.0 |  |  |
Proceeds from issuance of common stock | 5,000 |  |  |  |
Common stock premium | 200 |  |  |  |
Maximum eligible milestone payments receivable upon achievement of development, regulatory and commercial milestones | $ 438,000 |  |  |  |
Agreement termination prior written notice period | 6 months | 6 months |  |  |
Novartis Pharma AG [Member] | Gevokizumab License Agreement | Common Stock |  |  |  |  |
Licensing and other arrangements |  |  |  |  |
Shares issued (in shares) | shares | 539,131 | 539,131 |  |  |
Purchase price (in dollars per share) | $ / shares | $ 9.2742 |  |  |  |
Issuance of common stock, fair value | $ 4,800 |  |  |  |
Closing stock price (in dollars per share) | $ / shares | $ 8.93 |  |  |  |
Novartis Pharma AG [Member] | IL-1 Target License Agreement [Member] |  |  |  |  |
Licensing and other arrangements |  |  |  |  |
Cash payment received | $ 10,000 |  |  |  |

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