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Lease Agreements - Leased facilities (Details) - Leased facilities, Emeryville, California $ in Thousands | 12 Months Ended
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Dec. 31, 2022 USD ($) facility
Leases |
Operating leases, number of leased facilities | facility | 1
Net lease liability until expiration of lease | $ | $ 34

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
Name: | us-gaap_LesseeLeaseDescriptionLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Definition Amount of lessee's net lease liability until expiration of operating lease to be paid in next fiscal year following current fiscal year. Excludes payments after extension of lease. + References No definition available. + Details
Name: | xoma_LesseeOperatingLeaseLiabilityToBePaidYearOnePriorToExpirationOfLease
Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

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- Definition Operating leases, number of leased facilities. + References No definition available. + Details
Name: | xoma_OperatingLeasesNumberOfLeasedFacilities
Namespace Prefix: | xoma_
Data Type: | xbrli:integerItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | us-gaap_PropertyPlantAndEquipmentByTypeAxis=xoma_LeasedFacilitiesEmeryvilleCaliforniaMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |