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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2022
Income Taxes |
Schedule of Provision for Income Taxes (All Current) | The (benefit) provision for income taxes, all classified as current, consists of the following (in thousands): ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31,
​ |  | 2022 |  | 2021
Federal | ​ | $ | (15) | ​ | $ | 91
State | ​ |  | — | ​ |  | —
Total | ​ | $ | (15) | ​ | $ | 91
​
Reconciliation Between the Tax Provision Computed at the Federal Statutory Income Tax Rate and Actual Effective Income Tax Rate | Reconciliation between the tax provision computed at the federal statutory income tax rate and the Company’s actual effective income tax rate is as follows: ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31, |
​ |  | 2022 |  | 2021 |
Federal tax at statutory rate |  | 21 | % | 21 | %
Stock compensation and other permanent differences |  | (1) | % | 9 | %
Federal orphan drug credit |  | — | % | (2) | %
Tax benefit related to net operating loss carryforward utilization |  | — | % | (11) | %
Valuation allowance |  | (20) | % | (16) | %
Total |  | — | % | 1 | %
​
Components of Net Deferred Tax Assets | The significant components of net deferred tax assets at December 31, 2022 and 2021 were as follows (in thousands): ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31,
​ |  | 2022 |  | 2021
Capitalized research and development expenses | ​ | $ | 4,732 | ​ | $ | 7,822
Net operating loss carryforwards | ​ |  | 23,974 | ​ |  | 17,657
Research and development and other tax credit carryforwards | ​ |  | 13,176 | ​ |  | 13,125
Stock compensation | ​ |  | 4,715 | ​ |  | 4,778
Unearned revenue | ​ |  | 2,408 | ​ |  | 2,817
Other | ​ |  | 1,324 | ​ |  | 807
Total deferred tax assets | ​ |  | 50,329 | ​ |  | 47,006
Valuation allowance | ​ |  | (50,329) | ​ |  | (47,006)
Net deferred tax assets | ​ | $ | — | ​ | $ | —
​
Schedule of Unrecognized Tax Benefits | The following table summarizes the Company’s activity related to its unrecognized tax benefits (in thousands): ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31,
​ |  | 2022 |  | 2021
Balance at January 1 | ​ | $ | 5,938 | ​ | $ | 5,938
Increase related to current year tax position | ​ |  | — | ​ |  | —
Increase related to prior year tax position | ​ |  | — | ​ |  | —
Balance at December 31 | ​ | $ | 5,938 | ​ | $ | 5,938
​

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32639-109319 + Details
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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319 + Details
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