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Basis of Presentation and Significant Accounting Policies - Purchase of Rights to Future Milestones, Royalties, and Commercial Payments (Details) - USD ($) $ in Millions | Mar. 31, 2025 | Dec. 31, 2024
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Basis of Presentation and Significant Accounting Policies |  |
Purchased receivables included in royalty and commercial payment receivables, Effective interest rate method | $ 17.1 | $ 19.8
Purchased receivables included in royalty and commercial payment receivables, Cost recovery method | $ 1.5 | $ 1.3

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- References No definition available. + Details
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Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Amount, after allowance, of receivables related to income from purchased receivables under the cost recovery method due within one year or the normal operating cycle, if longer. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
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X
- Definition Amount, after allowance, of receivables related to income from purchased receivables under the effective interest rate method due within one year or the normal operating cycle, if longer. + References No definition available. + Details
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Namespace Prefix: | xoma_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant