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Consolidated Statements of Operations (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Dec. 31, 2021
Statement of Comprehensive Income [Abstract]        
Revenue     $ 0 $ 14,068
Operating expenses:        
Research and development $ 11,355 $ 13,781 49,418 60,923
General and administrative 9,156 9,477 33,584 37,176
Total operating expenses 20,511 23,258 83,002 98,099
Loss from operations (20,511) (23,258) (83,002) (84,031)
Interest income 523 95 1,327 397
Interest expense (284) (178) (961) (764)
Realized gain (loss) on investments     3 (23)
Foreign exchange (loss) gain     (5) 16
Other income (expense), net 753 (33) 1,056 (266)
Loss before income taxes (19,519) (23,374) (81,582) (84,671)
Income tax benefit (provision) (24) (12) 2 (15)
Net loss $ (19,543) $ (23,386) $ (81,580) $ (84,686)
Net loss per share attributable to common stockholders-basic and diluted $ (0.55) $ (0.67) $ (2.33) $ (2.47)
Weighteds Average Number Of Share Outstanding Basic And Diluted $ 35,324,053 $ 34,810,676 $ 35,075,924 $ 34,351,274