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Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Income Tax Disclosure [Abstract]

Schedule of Reconciliation Pre-tax Income

A reconciliation of the Company’s pre-tax loss for the years ended December 31, 2022 and 2021 is as follows:

		2022				2021
Domestic		$	(81,586	)		$	(84,624	)
Foreign			4				(47	)
Total		$	(81,582	)		$	(84,671	)

Schedule of Provision

The Company’s provision at December 31, 2022 and 2021 consist of the following:

		2022				2021
Current:
Federal		$	—			$	—
State			(2	)			15
Foreign			—				—
Total current		$	(2	)		$	15
Deferred:
Federal			—				—
State			—				—
Foreign			—				—
Total deferred		$	—			$	—
Total (benefit) provision		$	(2	)		$	15

Schedule of Reconciliation of U.S. Federal Statutory Income Tax Rate

A reconciliation of the U.S. federal statutory income tax rate to the Company’s effective income tax rate for the years ended December 31, 2022 and 2021 is as follows:

		2022				2021
U.S federal statutory income tax rate			21.0	%			21.0	%
Permanent differences			(0.1	)			—
State income taxes, net of federal benefit			5.4				2.7
Research and development tax credits			5.1				3.6
State rate changes			3.7				—
Stock compensation deductions			(2.8	)			1.6
Other items			—				(0.7	)
Change in deferred tax asset valuation allowance			(32.3	)			(28.2	)
Effective income tax rate			—	%			—	%

Schedule of Deferred Tax Assets

The Company’s deferred tax assets at December 31, 2022 and 2021 consist of the following:

		2022				2021
Deferred tax assets:
Net operating loss carryforwards		$	45,512			$	36,590
Research and development tax credits			11,163				7,026
Capitalized research and development costs			10,042				—
Intangibles			478				392
Stock compensation			9,507				6,554
Accrued expenses			—				107
Deferred revenue			—				—
Other			357				176
Fixed assets			282				265
Lease liability			7,735				7,269
Gross deferred tax asset			85,076				58,379
Valuation allowance			(77,288	)			(50,931	)
Net deferred tax assets		$	7,788			$	7,448
Deferred tax liabilities:
Right of use asset			(7,788	)			(7,448	)
Net deferred tax asset (liability)		$	—			$	—

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Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

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-Topic 740
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-Name Accounting Standards Codification
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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

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Tabular disclosure of income before income tax between domestic and foreign jurisdictions.

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-Topic 235
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
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