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Stock Based Compensation Expense Related to Employee Stock Options and Nonvested Restricted Common Stock Awards (Detail) (USD $)
6 Months Ended
Jun. 30, 2012
Jun. 25, 2011
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Stock-based compensation $ 2,223,828 $ 1,470,524
Cost of product revenues
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Stock-based compensation 265,503 296,866
Research and development
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Stock-based compensation 174,101 288,969
Selling, general and administrative
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Stock-based compensation $ 1,784,224 $ 884,689