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CONDENSED CONSOLIDATED STATEMENT OF OPERATIONS - USD ($)
 3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 24, 2016
Sep. 30, 2017
Sep. 24, 2016
Revenues:        
Net product revenues $ 5,589,402 $ 5,522,584 $ 14,501,945 $ 15,597,247
Research and development revenues 549,765 272,222 1,942,819 671,972
Total revenues 6,139,167 5,794,806 16,444,764 16,269,219
Expenses:        
Cost of product revenues 4,144,884 4,573,581 11,379,467 13,856,469
Research and development 5,253,860 4,123,268 14,213,950 12,282,620
Selling, general and administration 5,344,999 3,980,605 16,186,946 12,023,717
Gain on sale of property and plant 0 0 0 (7,700,522)
Total expenses 14,743,743 12,677,454 41,780,363 30,462,284
Loss from operations (8,604,576) (6,882,648) (25,335,599) (14,193,065)
Other income and expense:        
Interest income 191,613 191,472 611,532 532,185
Other (expense) income, net (109,546) (257,384) 215,883 (415,758)
Foreign currency transaction gains (losses) 224,370 (1,124,526) (410,373) (1,581,962)
Gain on investments 0 0 274,000 0
Total other income and expense 306,437 (1,190,438) 691,042 (1,465,535)
Loss before benefit (provision) for income taxes and net (income) loss attributable to noncontrolling interest (8,298,139) (8,073,086) (24,644,557) (15,658,600)
Tax benefit (provision) (4,500) (114,000) 1,141,500 (2,218,000)
Net loss (8,302,639) (8,187,086) (23,503,057) (17,876,600)
Net loss (income) attributable to the noncontrolling interest 55,217 69,782 65,223 (367,640)
Net loss attributable to the controlling interest $ (8,247,422) $ (8,117,304) $ (23,437,834) $ (18,244,240)
Net (loss) income per share        
Basic and diluted (usd per share) $ (0.11) $ (0.13) $ (0.34) $ (0.29)
Weighted average number of common shares        
Basic and diluted (in shares) 72,187,688 64,047,852 69,117,640 64,012,490