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CONDENSED CONSOLIDATED STATEMENT OF OPERATIONS - USD ($)
 3 Months Ended
Mar. 31, 2018
Apr. 01, 2017
Revenues:    
Net product revenues $ 5,044,809 $ 3,933,142
Research and development revenues 608,811 444,985
Total revenues 5,653,620 4,378,127
Expenses:    
Cost of product revenues 4,062,191 3,117,357
Research and development 4,451,653 4,281,870
Selling, general and administration 6,931,410 5,641,684
Total expenses 15,445,254 13,040,911
Loss from operations (9,791,634) (8,662,784)
Other income and expense:    
Interest income 159,851 233,777
Other income 1,101,255 534,411
Foreign currency transaction gains (losses) 208,608 (1,191,283)
Gain on investments 2,849,816 0
Total other income and expense 4,319,530 (423,095)
Loss before (provision) benefit for income taxes and net loss (income) attributable to noncontrolling interest (5,472,104) (9,085,879)
Tax benefit 0 1,146,000
Net loss (5,472,104) (7,939,879)
Net (income) loss attributable to noncontrolling interest (64,174) 81,438
Net loss attributable to the controlling interest $ (5,536,278) $ (7,858,441)
Net (loss) income per share    
Basic and diluted (usd per share) $ (0.08) $ (0.12)
Weighted average number of common shares    
Basic and diluted (in shares) 73,078,344 64,538,686