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Stockholders’ Equity (Details) - Schedule of special voting shares activity	6 Months Ended
	Jun. 30, 2021 shares
Schedule of special voting shares activity [Abstract]
Balance, January 1, 2021	1,469,417
Shares issued
Shares exchanged	(959,809)
Balance, June 30, 2021	509,608

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- References

No definition available.

+ Details

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Namespace Prefix:	atnf_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

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- Definition

Number of special voting shares exchanged.

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No definition available.

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Namespace Prefix:	atnf_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration

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- Definition

Number of special voting shares issued.

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No definition available.

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Name:	atnf_SpecialVotingShareIssued
Namespace Prefix:	atnf_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration

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- Definition

Number of special voting shares.

+ References

No definition available.

+ Details

Name:	atnf_SpecialVotingShares
Namespace Prefix:	atnf_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant