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Accrued Expenses (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued expenses - related parties	$ 103,494	$ 18,370

X

- Definition

The amount of accrued expenses - related parties.

+ References

No definition available.

+ Details

Name:	atnf_AccruedExpensesRelatedParties
Namespace Prefix:	atnf_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

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- References

No definition available.

+ Details

Name:	us-gaap_PayablesAndAccrualsAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration