<SEC-DOCUMENT>0001213900-23-090732-index.html : 20231129
<SEC-HEADER>0001213900-23-090732.hdr.sgml : 20231129
<ACCEPTANCE-DATETIME>20231129081009
ACCESSION NUMBER:		0001213900-23-090732
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		16
CONFORMED PERIOD OF REPORT:	20231128
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Unregistered Sales of Equity Securities
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20231129
DATE AS OF CHANGE:		20231129

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			180 Life Sciences Corp.
		CENTRAL INDEX KEY:			0001690080
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				813832378
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38105
		FILM NUMBER:		231448540

	BUSINESS ADDRESS:	
		STREET 1:		3000 EL CAMINO REAL
		STREET 2:		BLDG 4, STE 200
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94306
		BUSINESS PHONE:		650-507-0669

	MAIL ADDRESS:	
		STREET 1:		3000 EL CAMINO REAL
		STREET 2:		BLDG 4, STE 200
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94306

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	KBL MERGER CORP. IV
		DATE OF NAME CHANGE:	20161115
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>ea189187-8k_180life.htm
<DESCRIPTION>CURRENT REPORT
<TEXT>
Document 1 - file: ea189187-8k_180life.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.1
<SEQUENCE>2
<FILENAME>ea189187ex4-1_180life.htm
<DESCRIPTION>FORM OF WARRANT AGENT AGREEMENT FOR PRE-FUNDED WARRANTS AND COMMON WARRANTS
<TEXT>
Document 2 - file: ea189187ex4-1_180life.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.4
<SEQUENCE>3
<FILENAME>ea189187ex4-4_180life.htm
<DESCRIPTION>WARRANT AMENDMENT AGREEMENT, DATED NOVEMBER 28, 2023, BY AND BETWEEN THE COMPANY AND THE PURCHASER
<TEXT>
Document 3 - file: ea189187ex4-4_180life.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.1
<SEQUENCE>4
<FILENAME>ea189187ex10-1_180life.htm
<DESCRIPTION>AMENDMENT NO.1 TO THE SECURITIES PURCHASE AGREEMENT, DATED NOVEMBER 28, 2023, BY AND BETWEEN 180 LIFE SCIENCES CORP. AND THE PURCHASER
<TEXT>
Document 4 - file: ea189187ex10-1_180life.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-101.SCH
<SEQUENCE>5
<FILENAME>atnf-20231128.xsd
<DESCRIPTION>XBRL SCHEMA FILE
<TEXT>
Document 5 - file: atnf-20231128.xsd

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<DOCUMENT>
<TYPE>EX-101.DEF
<SEQUENCE>6
<FILENAME>atnf-20231128_def.xml
<DESCRIPTION>XBRL DEFINITION FILE
<TEXT>
Document 6 - file: atnf-20231128_def.xml

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<TYPE>EX-101.LAB
<SEQUENCE>7
<FILENAME>atnf-20231128_lab.xml
<DESCRIPTION>XBRL LABEL FILE
<TEXT>
Document 7 - file: atnf-20231128_lab.xml

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<TYPE>EX-101.PRE
<SEQUENCE>8
<FILENAME>atnf-20231128_pre.xml
<DESCRIPTION>XBRL PRESENTATION FILE
<TEXT>
Document 8 - file: atnf-20231128_pre.xml

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<SEQUENCE>9
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 9 - file: R1.htm

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<TYPE>XML
<SEQUENCE>10
<FILENAME>ea189187-8k_180life_htm.xml
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<TEXT>
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Document 10 - RAW XML: ea189187-8k_180life_htm.xml

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<DOCUMENT>
<TYPE>EXCEL
<SEQUENCE>11
<FILENAME>Financial_Report.xlsx
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 11 - file: Financial_Report.xlsx

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>12
<FILENAME>Show.js
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 12 - file: Show.js

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>13
<FILENAME>report.css
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 13 - file: report.css

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<DOCUMENT>
<TYPE>XML
<SEQUENCE>14
<FILENAME>FilingSummary.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 14 - file: FilingSummary.html

Document 14 - RAW XML: FilingSummary.xml

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<DOCUMENT>
<TYPE>JSON
<SEQUENCE>16
<FILENAME>MetaLinks.json
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 16 - file: MetaLinks.json

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<DOCUMENT>
<TYPE>ZIP
<SEQUENCE>17
<FILENAME>0001213900-23-090732-xbrl.zip
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 17 - file: 0001213900-23-090732-xbrl.zip

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