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<ACCEPTANCE-DATETIME>20240117083035
ACCESSION NUMBER:		0001213900-24-003899
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		17
CONFORMED PERIOD OF REPORT:	20240110
ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20240117
DATE AS OF CHANGE:		20240117

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			180 Life Sciences Corp.
		CENTRAL INDEX KEY:			0001690080
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				813832378
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38105
		FILM NUMBER:		24536801

	BUSINESS ADDRESS:	
		STREET 1:		3000 EL CAMINO REAL
		STREET 2:		BLDG 4, STE 200
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94306
		BUSINESS PHONE:		650-507-0669

	MAIL ADDRESS:	
		STREET 1:		3000 EL CAMINO REAL
		STREET 2:		BLDG 4, STE 200
		CITY:			PALO ALTO
		STATE:			CA
		ZIP:			94306

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	KBL MERGER CORP. IV
		DATE OF NAME CHANGE:	20161115
</SEC-HEADER>
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<FILENAME>ea191699-8k_180life.htm
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<FILENAME>ea191699ex10-1_180life.htm
<DESCRIPTION>FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT DATED JANUARY 10, 2024 AND EFFECTIVE AS OF JANUARY 1, 2024, BETWEEN 180 LIFE SCIENCES CORP. AND JAMES N. WOODY, M.D., PH.D
<TEXT>
Document 2 - file: ea191699ex10-1_180life.htm

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<FILENAME>ea191699ex10-2_180life.htm
<DESCRIPTION>FOURTH AMENDMENT TO EMPLOYMENT AGREEMENT DATED JANUARY 10, 2024 AND EFFECTIVE AS OF JANUARY 1, 2024, BETWEEN 180 LIFE SCIENCES CORP. AND JONATHAN ROTHBARD, PH.D
<TEXT>
Document 3 - file: ea191699ex10-2_180life.htm

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<TYPE>EX-10.3
<SEQUENCE>4
<FILENAME>ea191699ex10-3_180life.htm
<DESCRIPTION>THIRD AMENDMENT TO CONSULTING AGREEMENT DATED JANUARY 10, 2024 AND EFFECTIVE AS OF JANUARY 1, 2024, BETWEEN 180 LIFE SCIENCES CORP. AND LAWRENCE STEINMAN, M.D
<TEXT>
Document 4 - file: ea191699ex10-3_180life.htm

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<DOCUMENT>
<TYPE>EX-10.4
<SEQUENCE>5
<FILENAME>ea191699ex10-4_180life.htm
<DESCRIPTION>SECOND AMENDMENT TO CONSULTING AGREEMENT DATED JANUARY 10, 2024 AND EFFECTIVE AS OF JANUARY 1, 2024, BETWEEN CANNBIOREX PHARMA LTD. AND SIR MARC FELDMANN
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