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Income Taxes - Reconciliation of Effective Tax (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Income tax at statutory rate	$ (9,828)	$ (3,988)
State income taxes, net of Federal benefit	16	(132)
Research and development tax credit	(175)	(145)
Change in Federal tax rate due to tax reform	0	3,221
Meals and entertainment	416	338
Promissory note - debt discount	105	0
Revaluation of contingent royalty obligation	2,205	0
Meals and entertainment	17	3
Valuation allowance	7,309	(6,548)
Total provision (benefit) for income taxes	$ 65	$ (7,251)

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