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Term Loans - Pharmakon Term Loans (Details)	Dec. 14, 2021 USD ($) payment tranche	Mar. 15, 2019	Dec. 31, 2021 USD ($)
Term Loan
Debt Instrument [Line Items]
Interest rate on debt		9.50%
Debt instrument, prepayment amount threshold			$ 20,000
Term Loan | LIBOR
Debt Instrument [Line Items]
Basis spread on variable rate		7.00%
Pharmakon Term Loans
Debt Instrument [Line Items]
Number of tranches | tranche	2
Pharmakon Term Loans | Term Loan
Debt Instrument [Line Items]
Debt instrument, face amount			$ 125,000,000
Interest rate on debt	1.00%
Number of periodic payments | payment	12
Debt discount	$ 3,042,000
Debt issuance costs	$ 3,263,000
Interest rate, effective percentage			10.89%
Pharmakon Term Loans | Term Loan | LIBOR
Debt Instrument [Line Items]
Basis spread on variable rate	8.50%
Tranche A Loan | Term Loan
Debt Instrument [Line Items]
Debt instrument, face amount			$ 75,000,000
Anniversary period	39 months
Tranche A Loan | Term Loan | Prior to the 3rd anniversary
Debt Instrument [Line Items]
Debt instrument, percentage of principal amount, prepaid multiplied	3.00%
Tranche A Loan | Term Loan | After the 3rd anniversary but prior to the 4th anniversary
Debt Instrument [Line Items]
Debt instrument, percentage of principal amount, prepaid multiplied	2.00%
Tranche A Loan | Term Loan | After the 4th anniversary
Debt Instrument [Line Items]
Debt instrument, percentage of principal amount, prepaid multiplied	1.00%
Tranche B Loan | Term Loan
Debt Instrument [Line Items]
Debt instrument, face amount			$ 50,000,000

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