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Term Loans - Oxford Term Loans (Details)			3 Months Ended		9 Months Ended
	Jan. 04, 2021 USD ($)	Mar. 15, 2019 USD ($) advance	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)
Debt Instrument [Line Items]
Loss from extinguishment of debts, net			$ 0	$ 0	$ 0	$ 968,000
Term Loan Facility
Debt Instrument [Line Items]
Percentage of final payment of full principal amount		5.50%
Prepayment fee percentage, year two		2.00%
Prepayment fee percentage, thereafter		1.00%
Oxford Term Loan Facility
Debt Instrument [Line Items]
Repayments of long-term lines of credit	$ 76,447,000
Debt instrument fee amount comprised	4,300,000
Debt instrument of principal amount payment	2,800,000
Debt instrument prepayment fee amount	$ 1,500,000
Loss from extinguishment of debts, net						$ 1,939,000
Secured Debt
Debt Instrument [Line Items]
Contingent promissory note payable		$ 100,000,000
Number of advances | advance		2
Interest rate on debt		9.50%
Period of interest only payments		36 months
Amortization period		23 months
Secured Debt | London Interbank Offered Rate (LIBOR)
Debt Instrument [Line Items]
Basis spread on variable rate		7.00%
Secured Debt | First tranche
Debt Instrument [Line Items]
Contingent promissory note payable		$ 75,000,000
Secured Debt | Second tranche
Debt Instrument [Line Items]
Contingent promissory note payable		$ 25,000,000

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