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Commitment and Contingencies (Details) € in Thousands |  |  |  |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
May 09, 2023 EUR (€) product | Nov. 17, 2021 officer | Dec. 02, 2020 plaintiff | Oct. 28, 2020 complaint | Oct. 31, 2024 milestonePayment product | Jun. 30, 2023 USD ($) | Dec. 31, 2024 USD ($) product | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2024 EUR (€) | Dec. 31, 2024 USD ($) | Dec. 20, 2023 EUR (€) milestonePayment
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Inventory payments | $ |  |  |  |  |  |  | $ 62,233,000 | $ 50,770,000 | $ 50,685,000 |  |  |
Loss contingency, new claims filed, number | complaint |  |  |  | 2 |  |  |  |  |  |  |  |
Loss contingency, number of defendants, officers | officer |  | 3 |  |  |  |  |  |  |  |  |  |
Loss contingency, number of plaintiffs | plaintiff |  |  | 2 |  |  |  |  |  |  |  |  |
Loss contingency accrual | $ |  |  |  |  |  |  |  |  |  |  | $ 0 |
Symatese U.S. Agreement |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payment | € 16,200 |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement, initial payment | € 4,100 |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement, initial payment due, period | 30 days |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement payment, June 2025 (in euro) | € 1,600 |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement payment, June 2026 (in euro) | 4,100 |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement payment, June 2027 (in euro) | 3,200 |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement payment, June 2028 (in euro) | € 3,200 |  |  |  |  |  |  |  |  |  |  |
Annual payment triggered, number of products with regulatory approval | product | 3 |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement, upfront payment | $ |  |  |  |  |  | $ 4,441,000 |  | $ 4,441,000 |  |  |  |
Symatese Europe Agreement |  |  |  |  |  |  |  |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
License, supply and distribution agreement payment, June 2026 (in euro) |  |  |  |  |  |  |  |  |  |  |  | € 1,200
License, supply and distribution agreement payment, June 2027 (in euro) |  |  |  |  |  |  |  |  |  |  |  | € 1,900
Number of milestone payment | milestonePayment |  |  |  |  | 2 |  |  |  |  |  |  | 2
Annual revenue (in euro) |  |  |  |  |  |  |  |  |  | € 25,000 |  | € 25,000
Regulatory approval, number of products | product |  |  |  |  | 3 |  | 4 |  |  |  |  |
Milestone payment, payable period |  |  |  |  | 2 years |  |  |  |  |  |  |

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