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v3.26.1

Description of Business (Details) $ in Thousands |  |  | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
May 05, 2025 USD ($) tranche | Mar. 08, 2023 USD ($) | Oct. 31, 2024 product | Mar. 31, 2026 USD ($) product shares | Mar. 31, 2025 USD ($) | Mar. 03, 2026 USD ($) | Dec. 31, 2025 USD ($)
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Operating net loss |  |  |  | $ 6,848 | $ 15,172 |  |
Net loss |  |  |  | 10,674 | 18,892 |  |
Net cash used in operating activities |  |  |  | 9,952 | $ 15,632 |  |
Cash and cash equivalents |  |  |  | 49,792 |  |  | $ 53,826
Accumulated deficit |  |  |  | $ 671,714 |  |  | $ 661,040
ATM Sales Agreement |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Maximum consideration receivable |  | $ 50,000 |  |  |  |  |
Number of shares issued in transaction | shares |  |  |  | 0 |  |  |
New Pharmakon Term Loans | Line of Credit | Secured Debt |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Maximum borrowing capacity | $ 250,000 |  |  |  |  |  |
Number of tranches | tranche | 3 |  |  |  |  |  |
New Pharmakon Term Loans | Line of Credit | Revolving Credit Facility |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Maximum borrowing capacity, option | $ 40,000 |  |  |  |  |  |
A&R Loan Agreement, Tranche One | Line of Credit | Secured Debt |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Debt drawn | 150,000 |  |  |  |  |  |
A&R Loan Agreement, Tranche Two | Line of Credit | Secured Debt |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Maximum borrowing capacity | 50,000 |  |  |  |  |  |
A&R Loan Agreement, Tranche Three | Line of Credit | Secured Debt |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Maximum borrowing capacity | $ 50,000 |  |  |  |  |  |
Revolving Credit Facility | Line of Credit | Revolving Credit Facility |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Maximum borrowing capacity |  |  |  |  |  | $ 30,000 |
Line of credit facility, accordion feature, maximum limit |  |  |  |  |  | 10,000 |
Uncommitted accordion feature, electable increment amount |  |  |  |  |  | 5,000 |
Minimum utilization threshold, amount |  |  |  |  |  | $ 10,000 |
Symatese Europe Agreement |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Regulatory approval, number of products | product |  |  | 3 | 4 |  |  |
Symatese U.S. Agreement |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Expected regulatory approval, number of products | product |  |  |  | 2 |  |  |

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