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Shareholders’ Equity - Narrative (Details)
 3 Months Ended
Mar. 08, 2024
USD ($)
shares
Jul. 10, 2023
USD ($)
Jul. 09, 2023
USD ($)
shares
Jun. 30, 2023
USD ($)
Jun. 27, 2023
USD ($)
$ / shares
shares
Mar. 31, 2025
USD ($)
vote
$ / shares
shares
Mar. 31, 2024
shares
Dec. 31, 2024
$ / shares
shares
Dec. 31, 2023
shares
Aug. 31, 2023
USD ($)
May 11, 2023
USD ($)
Apr. 28, 2021
shares
Class of Stock [Line Items]                        
Common stock, conversion ratio (in shares)           33.638698            
Sale of stock, stamp duty tax | $   $ (2,800,000)                    
Stock options exercised (in shares)           93,347            
May 2023 Sales Agreement | ATM Shares                        
Class of Stock [Line Items]                        
Sale of stock, authorized amount (in shares) | $                     $ 200,000,000.0  
Sale of stock, remaining authorized repurchase amount | $         $ 0              
May 2023 And August 2023 Sales Agreement | ATM Shares                        
Class of Stock [Line Items]                        
Sale of stock, authorized amount (in shares) | $                   $ 350,000,000.0    
August 2023 Sales Agreement | ATM Shares                        
Class of Stock [Line Items]                        
Sale of stock, authorized amount (in shares) | $           $ 265,000,000.0            
MoonLake AG                        
Class of Stock [Line Items]                        
Common shares, shares outstanding (in shares)                       110,000
MoonLake AG | MoonLake Immunotherapeutics                        
Class of Stock [Line Items]                        
Net proceeds from the business combination | $ $ 800,000   $ 38,900,000                  
Proceeds from contributions from parent | $ 150,000,000 $ 275,000,000                    
Sale of stock, stamp duty tax | $ $ (1,600,000)                      
Underwriting Agreement                        
Class of Stock [Line Items]                        
Sale of stock (in shares)         8,000,000              
Net proceeds from the business combination | $       $ 436,700,000                
Issuance price per share (USD per share) | $ / shares         $ 50.00              
Payments of stock issuance costs | $       $ 23,300,000                
Underwriting Agreement | MoonLake AG | MoonLake Immunotherapeutics                        
Class of Stock [Line Items]                        
Sale of stock (in shares) 501   22,756                  
Over-Allotment Option                        
Class of Stock [Line Items]                        
Sale of stock (in shares)         1,200,000              
Sale of stock, option to purchase, term         30 days              
Sales Agreements                        
Class of Stock [Line Items]                        
Net proceeds from the business combination | $           $ 0            
Common Stock | MoonLake AG                        
Class of Stock [Line Items]                        
Treasury stock, shares, acquired (in shares) 501                      
Common Class A                        
Class of Stock [Line Items]                        
Common shares, shares issued (in shares)           63,474,253   63,077,431        
Common shares, shares outstanding (in shares)           63,474,253   63,077,431        
Common shares, shares authorized (in shares)           500,000,000   500,000,000        
Common shares, par value (USD per share) | $ / shares           $ 0.0001   $ 0.0001        
Common Class A | Common Stock                        
Class of Stock [Line Items]                        
Common shares, shares issued (in shares)           63,474,253   63,077,431        
Common shares, shares outstanding (in shares)           63,474,253 62,874,637 63,077,431 60,466,453      
Common shares, shares authorized (in shares)           500,000,000   500,000,000        
Common shares, par value (USD per share) | $ / shares           $ 0.0001            
Common shares, votes per share | vote           1            
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           111,949 1,493,356          
Stock options exercised (in shares)           93,347            
Common Class A | Common Stock | Conversion Of Class C into Class A                        
Class of Stock [Line Items]                        
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           111,949            
Common Class A | Common Stock | A&R Shareholders Agreement                        
Class of Stock [Line Items]                        
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           111,949            
Common Class C                        
Class of Stock [Line Items]                        
Common shares, shares issued (in shares)           729,320   841,269        
Common shares, shares outstanding (in shares)           729,320   841,269        
Common shares, shares authorized (in shares)           100,000,000   100,000,000        
Common shares, par value (USD per share) | $ / shares           $ 0.0001   $ 0.0001        
Common Class C | MoonLake AG                        
Class of Stock [Line Items]                        
Common shares, shares outstanding (in shares)                       3,700,257
Common Class C | Common Stock                        
Class of Stock [Line Items]                        
Common shares, shares issued (in shares)           729,320   841,269        
Common shares, shares outstanding (in shares)           729,320 995,267 841,269 2,505,476      
Common shares, shares authorized (in shares)           100,000,000   100,000,000        
Common shares, par value (USD per share) | $ / shares           $ 0.0001            
Common shares, votes per share | vote           1            
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           (111,949) (1,493,356)          
Common Class C | Common Stock | Conversion Of Class C into Class A                        
Class of Stock [Line Items]                        
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           (111,949)            
Common Class C | Common Stock | A&R Shareholders Agreement                        
Class of Stock [Line Items]                        
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           111,949            
Common Class C | Common Stock | MoonLake AG                        
Class of Stock [Line Items]                        
Treasury stock, shares, acquired (in shares) 16,853                      
MoonLake AG | Common Stock | A&R Shareholders Agreement                        
Class of Stock [Line Items]                        
Conversion of MoonLake Class C Ordinary Shares into Class A Ordinary Shares (in shares)           3,328