XML 84 R75.htm IDEA: XBRL DOCUMENT v3.20.4
Licensing And Collaboration Agreements - Additional Information (Detail)
¥ in Thousands, $ in Thousands
1 Months Ended 9 Months Ended 12 Months Ended
Sep. 03, 2020
USD ($)
Feb. 28, 2019
CNY (¥)
Jan. 01, 2018
Nov. 17, 2017
CNY (¥)
Nov. 17, 2017
USD ($)
Dec. 31, 2020
USD ($)
Aug. 31, 2020
CNY (¥)
Aug. 31, 2020
USD ($)
Jan. 31, 2020
CNY (¥)
shares
Jan. 31, 2020
USD ($)
shares
Sep. 30, 2020
CNY (¥)
shares
Sep. 30, 2020
USD ($)
Sep. 30, 2019
CNY (¥)
Sep. 30, 2019
USD ($)
Dec. 31, 2020
CNY (¥)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
CNY (¥)
shares
Dec. 31, 2019
USD ($)
Dec. 31, 2018
CNY (¥)
Dec. 31, 2018
USD ($)
Dec. 31, 2017
CNY (¥)
Dec. 31, 2017
USD ($)
Sep. 30, 2020
USD ($)
shares
Jan. 17, 2020
shares
Nov. 04, 2019
CNY (¥)
shares
Nov. 04, 2019
USD ($)
shares
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense                     ¥ 698,461 $ 102,872 ¥ 578,377                          
Issue of shares, Value                     ¥ 106           ¥ 6           $ 16      
Issue of shares | shares                     153,543,910           8,363,719           153,543,910      
Milestone revenue recognized | ¥                         30,000                          
Licensing Agreement With CSPC Pharmaceutical Group Limited [Member] | CSPC [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee | ¥                     ¥ 15,000               ¥ 15,000              
Milestone payments | ¥                     15,000                              
Advance from customers | ¥                                     14,200              
Proceeds from milestone achievement | ¥   ¥ 800                 15,000                              
Milestone revenue recognized | ¥                                 ¥ 30,000                  
Milestone income | ¥   ¥ 800                 15,000                              
Licensing Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                       0       $ 0                    
Revenue from collaborative arrangement, excluding assessed tax                       $ 0   $ 0                        
Milestone revenue recognized                                     17,200 $ 2,500            
Licensing Agreement With ABL Bio [Member] | ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                 ¥ 690,300 $ 97,500                                
Licensing Agreement With ABL Bio [Member] | ABL Bio [Member] | Clinical Milestones [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                 ¥ 230,100 $ 32,500                                
Collaboration Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense | ¥                     ¥ 26,000   6,300       12,200                  
Cost sharing ratio                     50.00% 50.00%                            
Collaboration Agreement With ABL Bio [Member] | ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense | ¥                                 8,000                  
Licensing Agreement with MorphoSys AG [Member] | MorphoSys [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                     ¥ 132,700 $ 20,000                            
Licensing Agreement with Genexine Inc [Member] | Genexine Inc [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Reduction in milestone payment     50.00%                                              
Licensing Agreement with Genexine Inc [Member] | Genexine Inc [Member] | GXI7 [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                       2,000,000                            
Licensing Agreement with MorphoSy [Member] | MorphoSysAG [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments       ¥ 653,500 $ 98,500                                          
Licensing Agreement with MacroGenics [Member] | MacroGenics [Member] | Development Milestone [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                                   $ 75,000                
Other In-Licensing Arrangements [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                       400                            
Milestone payments due | ¥                     8,200                              
Licensing Agreement among HDYM, I-Mab and Hangzhou HealSun Biopharm Co., Ltd [Member] | HealSun [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments income | ¥                     51,000                              
Research and Development Expense [Member] | Licensing Agreement with MorphoSys AG [Member] | MorphoSys [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                                       0 ¥ 132,700 $ 20,000        
Milestone payments                                 55,700 8,000                
Research and Development Expense [Member] | Licensing Agreement with Genexine Inc [Member] | Genexine Inc [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                       12,000                            
Milestone payments | ¥                             ¥ 152,600                      
Research and Development Expense [Member] | Licensing Agreement with MacroGenics [Member] | MacroGenics [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                                   15,000                
Operating Expense [Member] | Licensing Agreement With ABL Bio [Member] | ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense                     150 20         1,400                  
Operating Expense [Member] | Collaboration Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense | ¥                     12,400   6,000                          
Operating Expense [Member] | Collaboration Agreements with Tracon Pharmaceuticals Inc [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense                     200 30 24,300 3,400     27,800 4,000                
Other In Licensing Agreements [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                                 8,400 1,200                
Milestone payments                     2,900 1,200                            
Milestone payments due                     1,144,500 164,400         10,500 1,500                
MorphoSysAG [Member] | Licensing Agreement with MorphoSys AG [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments             ¥ 6,800 $ 1,000                                    
MorphoSysAG [Member] | Research and Development Expense [Member] | Licensing Agreement with MorphoSys AG [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                               0     ¥ 23,200 $ 3,500            
Genexine Inc [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development costs capitalised | ¥                     1,400                              
Genexine Inc [Member] | Licensing Agreement with Genexine Inc [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                       $ 525,000         3,482,700                  
Long-term Purchase Commitment, Period                                     15 years 15 years            
Genexine Inc [Member] | Research and Development Expense [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development costs capitalised | ¥                     900                              
Genexine Inc [Member] | Research and Development Expense [Member] | Licensing Agreement with Genexine Inc [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee | ¥                     ¥ 79,600                              
Milestone payments                                   23,000                
MacroGenics [Member] | Licensing Agreement with MacroGenics [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Licensing Arrangements, Description of terms                     The Group is responsible for all development costs in Greater China. MacroGenics is responsible for all development costs in the rest of the world, except that the Group is responsible for 20% of the costs incurred in (i) activities supporting global clinical trials in which the Group participates, (ii) certain CMC activities for material intended to be used in clinical trials in Greater China, and (iii) companion diagnostic development and validation for indications being studied in Greater China. The Group is responsible for all development costs in Greater China. MacroGenics is responsible for all development costs in the rest of the world, except that the Group is responsible for 20% of the costs incurred in (i) activities supporting global clinical trials in which the Group participates, (ii) certain CMC activities for material intended to be used in clinical trials in Greater China, and (iii) companion diagnostic development and validation for indications being studied in Greater China.                            
MacroGenics [Member] | Licensing Agreements [Member] | Research and Development Expense [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee | ¥                                 104,400                  
MacroGenics [Member] | Licensing Agreements [Member] | Research and Development Expense [Member] | Minimum [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                                   60,000                
Everest [Member] | Collaboration Agreement with Everest [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense                                 ¥ 51,600 $ 7,600                
Shares issued upon conversion | shares                 6,078,571 6,078,571                           6,078,571    
Everest [Member] | Out Licensing Agreements [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Description of Payment Terms                     Under the agreement, the Group is primarily responsible for carrying out the development, manufacture and supply of the CD38 product, as well as seeking regulatory approval of the CD38 product. Everest is primarily responsible for sharing the development costs of the CD38 product, including payments due to MorphoSys under the Licensing Agreement, dated November 30, 2017, in the proportion of 75% by Everest and 25% by the Group. Under the agreement, the Group is primarily responsible for carrying out the development, manufacture and supply of the CD38 product, as well as seeking regulatory approval of the CD38 product. Everest is primarily responsible for sharing the development costs of the CD38 product, including payments due to MorphoSys under the Licensing Agreement, dated November 30, 2017, in the proportion of 75% by Everest and 25% by the Group.                            
Sharing the profit and loss                     (5.00%)                       (5.00%)      
Research and development expense                                     ¥ 178,700 $ 26,000            
Issue of shares, Value                                                 ¥ 258,100 $ 37,000
Issue of shares | shares                                                 4,762,751 4,762,751
Cumulative Paid In Contributions                                                   $ 33,700
Time cost of foregoing historical contribution                                                 ¥ 23,000 $ 3,300
ABL Bio [Member] | Licensing Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee                 ¥ 17,200 $ 2,500                                
ABL Bio [Member] | Licensing Agreement With ABL Bio [Member] | Sales Milestones [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone payments                 ¥ 460,200 $ 65,000                                
ABL Bio [Member] | Research and Development Expense [Member] | Licensing Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense                               200                    
ABL Bio [Member] | Operating Expense [Member] | Licensing Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense                     ¥ 300 $ 40 ¥ 700 $ 100                        
Cost sharing ratio                         50.00% 50.00%                        
ABL Bio [Member] | Operating Expense [Member] | Collaboration Agreement With ABL Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Research and development expense | ¥                     ¥ 39,600   ¥ 6,600                          
KG Bio [Member] | Licensing Agreement with KG Bio [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Milestone income                       340,000                            
AbbVie [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront License Fee $ 180,000                                                  
Milestone payments 20,000                                                  
Proceeds from milestone achievement 1,740,000                                                  
Milestone income 1,740,000                                                  
Upfront payment received                       $ 180,000                            
AbbVie [Member] | Subsequent Event [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Upfront payment received           $ 180,000                                        
Milestone Payment Receivable           $ 20,000                   $ 20,000                    
AbbVie [Member] | Clinical Milestones [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Proceeds from milestone achievement 840,000                                                  
Milestone income 840,000                                                  
AbbVie [Member] | Minimum [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Potential value of license agreement 500,000                                                  
AbbVie [Member] | Maximum [Member]                                                    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                                    
Potential value of license agreement $ 1,000,000