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Research and Collaboration Arrangements - CRF Agreement - Additional Information (Details) - CRF - CRF Agreement - USD ($) | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Nov. 30, 2015 | Dec. 31, 2021 | Dec. 31, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |
Collaborative arrangement, initial research term | 2 years |  |
Collaborative arrangement contribution upon development milestone | $ 2,500,000 |  |
Collaborative arrangement additional research term | 3 years |  |
Collaborative arrangement achieved milestones |  | $ 0 |
Deferred revenue |  | 0 | $ 0
Due from related parties |  | 0 | 0
Amount due to related party |  | $ 0 | $ 0

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