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Research and Collaboration Arrangements - CRF Agreement - Additional Information (Details) - CRF - CRF Agreement - USD ($)	1 Months Ended	12 Months Ended
	Nov. 30, 2015	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative arrangement, initial research term	2 years
Collaborative arrangement contribution upon development milestone	$ 2,500,000
Collaborative arrangement additional research term	3 years
Collaborative arrangement achieved milestones		$ 0
Deferred revenue		0	$ 0
Due from related parties		0	0
Amount due to related party		$ 0	$ 0

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