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Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities    
Net loss $ (71,317) $ (56,693)
Adjustments to reconcile net loss to net cash used in operating activities    
Stock-based compensation expense 13,799 4,984
Vesting of common stock warrant in return for services 87 48
Change in fair value of derivative liability 92 21
Depreciation and amortization 1,523 1,443
Amortization of right-of-use assets 1,497 0
Net amortization (accretion) of premium (discount) on marketable securities 719 0
Changes in operating assets and liabilities    
Accounts receivable 1,439 (508)
Prepaid expenses and other current assets (4,225) (2,566)
Other assets 0 75
Accounts payable 2,285 43
Accrued and other liabilities 689 1,899
Deferred revenue (14,722) 345
Operating lease liabilities (1,000) 0
Net cash used in operating activities (69,134) (50,909)
Cash flows from investing activities    
Acquisition of property and equipment (9,110) (1,000)
Purchase of marketable securities (168,570) 0
Maturities of marketable securities 5,000 0
Net cash used in investing activities (172,680) (1,000)
Cash flows from financing activities    
Issuance of redeemable convertible preferred stock, net of issuance costs 0 72,468
Issuance of common stock upon offerings, net of issuance costs 114,296 205,658
Issuance of common stock upon exercise of stock options and warrants 3,360 857
Issuance of common stock through 2020 ESPP 433 0
Net cash provided by financing activities 118,089 278,983
Net (decrease) increase in cash and cash equivalents (123,725) 227,074
Cash and cash equivalents, beginning of period 276,726 49,652
Cash and cash equivalents, end of period 153,001 276,726
Supplemental disclosures of noncash investing and financing information    
Conversion of redeemable convertible preferred stock into common stock 0 175,448
Purchases of property and equipment in accounts payable and accrued and other liabilities 2,199 466
Unpaid offering costs 152 946
Decrease in right-of-use assets due to reduction in operating lease liabilities upon modification (478) 0
Issuance of common stock warrant to settle liability 1,146 0
Receivable for common stock issued upon exercise of stock options $ 545 $ 0