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Segment Reporting | 12 Months Ended
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Dec. 31, 2025
Segment Reporting [Abstract] |
Segment Reporting | 15. Segment Reporting Segment reporting is prepared on the same basis that the Company's Chief Executive Officer, who is its chief operating decision maker, or CODM, manages the business and makes operating decisions to allocate resources across departments and functions in line with the Company's strategic goals. The Company operates in one reportable segment which includes all activities related to the research and development of ocular and urologic oncology targeted therapies for a range of cancer indications with high unmet medical need. The CODM assesses performance and allocates resources based on comparing actual consolidated net loss to the budget. The measure of segment assets used in determining how to manage and allocate resources is reported within the Company's consolidated balance sheets as cash and cash equivalents and marketable securities. As a single reportable segment entity, the Company’s segment performance measure is consolidated net loss. Significant segment expenses are presented below.
|  | Year Ended December 31, |
|  | 2025 |  |  | 2024 |
|  | (in thousands) |
Clinical, Preclinical, and R&D Operations (1) |  | $ | (63,154 | ) |  | $ | (49,550 | )
Chemistry, Manufacturing, and Controls (1) |  |  | (27,145 | ) |  |  | (23,752 | )
General and Administrative (1) |  |  | (22,491 | ) |  |  | (22,814 | )
Other Segment Items (2) |  |  | 6,599 |  |  |  | 9,197 |
Net loss |  | $ | (106,191 | ) |  | $ | (86,919 | )
(1) Includes depreciation expense directly allocated to respective activities. (2) Other segment items primarily include interest and accretion income, realized gains and losses, and income taxes.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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