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Income Taxes - Additional Information (Details) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024
Operating Loss Carryforwards [Line Items] |  |
Tax provision | $ 108,000 | $ 112,000
Income taxes paid | 100,000 | 100,000
Deferred tax assets, valuation allowance | 145,732,000 | 105,851,000
Increase in valuation allowance | 39,900,000 |
Unrecognized tax benefits | 0 | 0
Gross deferred tax assets | 150,548,000 | $ 111,146,000
Federal |  |
Operating Loss Carryforwards [Line Items] |  |
Accumulated net operating loss carryforwards | 318,900,000 |
Operating loss carryforwards not subject to expiration | $ 286,500,000 |
Federal | Earliest Tax Year |  |
Operating Loss Carryforwards [Line Items] |  |
Operating loss carryforwards begin to expire period | 2034 |
Federal | Latest Tax Year |  |
Operating Loss Carryforwards [Line Items] |  |
Operating loss carryforwards begin to expire period | 2037 |
Federal | 2034 Through 2037 |  |
Operating Loss Carryforwards [Line Items] |  |
Operating loss carryforwards subject to expiration | $ 32,400,000 |
Federal | Research and Development |  |
Operating Loss Carryforwards [Line Items] |  |
Tax Credit Carryforward | $ 8,500,000 |
Tax credit carryforwards begin to expire period | 2038 |
Federal | Orphan Drug Credits |  |
Operating Loss Carryforwards [Line Items] |  |
Tax Credit Carryforward | $ 20,400,000 |
Tax credit carryforwards begin to expire period | 2039 |
Increase in credit carryforwards | $ 12,100,000 |
State |  |
Operating Loss Carryforwards [Line Items] |  |
Accumulated net operating loss carryforwards | 274,400,000 |
Operating loss carryforwards not subject to expiration | $ 2,200,000 |
Operating loss carryforwards begin to expire period | 2030 |
State | Research and Development |  |
Operating Loss Carryforwards [Line Items] |  |
Tax Credit Carryforward | $ 3,800,000 |
Tax credit carryforwards begin to expire period | 2034 |
State | Orphan Drug Credits |  |
Operating Loss Carryforwards [Line Items] |  |
Increase in credit carryforwards | $ 200,000 |

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