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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2025
Share-Based Payment Arrangement [Abstract] |
Summary of Combined Stock Option Activity under 2018 Plan and 2021 Plan | The following table summarizes stock option activity under the 2018 Plan and 2021 Plan for the year ended December 31, 2025:
|  | Options |  |  | Weighted- Average Exercise Price |  |  | Weighted- Average Remaining Contractual Term (years) |  |  | Aggregate Intrinsic Value (in thousands) |
Outstanding at December 31, 2024 |  |  | 5,522,353 |  |  | $ | 8.17 |  |  |  | 6.91 |  |  | $ | 8,068 |
Granted |  |  | 1,596,043 |  |  |  | 7.14 |  |  |  |  |  |  |
Exercised |  |  | (247,993 | ) |  |  | 4.30 |  |  |  |  |  |  |
Cancelled/Forfeited |  |  | (402,821 | ) |  |  | 10.35 |  |  |  |  |  |  |
Outstanding at December 31, 2025 |  |  | 6,467,582 |  |  | $ | 7.93 |  |  |  | 6.96 |  |  | $ | 1,503 |
Exercisable at December 31, 2025 |  |  | 3,908,454 |  |  | $ | 8.07 |  |  |  | 5.79 |  |  | $ | 1,503 |
Schedule of Fair Value of Stock Options, Valuation Assumptions | The fair value of the stock options issued as of December 31, 2025 and 2024 was measured with the following weighted-average assumptions:
| Year Ended December 31, |
| 2025 |  |  | 2024 |
Risk-free interest rate |  | 4.26 | % |  |  | 3.93 | %
Expected term (years) |  | 6.05 |  |  |  | 6.03 |
Expected volatility of the underlying stock |  | 91.65 | % |  |  | 88.63 | %
Expected dividend rate |  | — | % |  |  | — | %
Schedule of Nonvested Restricted Stock Units Activity | A summary of the restricted stock units activity during the year ended December 31, 2025 is as follows:
|  | Restricted Stock Units |  |  | Weighted- Average Grant Date Fair Value |
Unvested at December 31, 2024 |  |  | 1,589,042 |  |  | $ | 8.76 |
Granted |  |  | 1,837,279 |  |  |  | 7.30 |
Vested/Released |  |  | (532,401 | ) |  |  | 9.01 |
Forfeited |  |  | (203,143 | ) |  |  | 8.46 |
Unvested at December 31, 2025 |  |  | 2,690,777 |  |  | $ | 7.74 |
Summary of Stock-Based Compensation Expense | The Company recorded stock-based compensation expense as follows (in thousands):
|  | Year Ended December 31, |
|  | 2025 |  |  | 2024 |
Research and development |  | $ | 7,825 |  |  | $ | 5,696 |
General and administrative |  |  | 6,492 |  |  |  | 6,026 |
Total |  | $ | 14,317 |  |  | $ | 11,722 |

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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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