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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Summary of Combined Stock Option Activity under 2018 Plan and 2021 Plan

The following table summarizes stock option activity under the 2018 Plan and 2021 Plan for the year ended December 31, 2025:

 

Options

 

 

Weighted-
Average
Exercise
Price

 

 

Weighted-
Average
Remaining
Contractual
Term
(years)

 

 

Aggregate Intrinsic
Value
(in thousands)

 

Outstanding at December 31, 2024

 

 

5,522,353

 

 

$

8.17

 

 

 

6.91

 

 

$

8,068

 

Granted

 

 

1,596,043

 

 

 

7.14

 

 

 

 

 

 

 

Exercised

 

 

(247,993

)

 

 

4.30

 

 

 

 

 

 

 

Cancelled/Forfeited

 

 

(402,821

)

 

 

10.35

 

 

 

 

 

 

 

Outstanding at December 31, 2025

 

 

6,467,582

 

 

$

7.93

 

 

 

6.96

 

 

$

1,503

 

Exercisable at December 31, 2025

 

 

3,908,454

 

 

$

8.07

 

 

 

5.79

 

 

$

1,503

 

Schedule of Fair Value of Stock Options, Valuation Assumptions

The fair value of the stock options issued as of December 31, 2025 and 2024 was measured with the following weighted-average assumptions:

Year Ended
December 31,

 

 

2025

 

 

2024

 

Risk-free interest rate

 

4.26

%

 

 

3.93

%

Expected term (years)

 

6.05

 

 

 

6.03

 

Expected volatility of the underlying stock

 

91.65

%

 

 

88.63

%

Expected dividend rate

 

%

 

 

%

Schedule of Nonvested Restricted Stock Units Activity

A summary of the restricted stock units activity during the year ended December 31, 2025 is as follows:

 

 

Restricted Stock Units

 

 

Weighted-
Average
Grant Date Fair Value

 

Unvested at December 31, 2024

 

 

1,589,042

 

 

$

8.76

 

Granted

 

 

1,837,279

 

 

 

7.30

 

Vested/Released

 

 

(532,401

)

 

 

9.01

 

Forfeited

 

 

(203,143

)

 

 

8.46

 

Unvested at December 31, 2025

 

 

2,690,777

 

 

$

7.74

 

Summary of Stock-Based Compensation Expense

The Company recorded stock-based compensation expense as follows (in thousands):

 

Year Ended
December 31,

 

 

 

2025

 

 

2024

 

Research and development

 

$

7,825

 

 

$

5,696

 

General and administrative

 

 

6,492

 

 

 

6,026

 

Total

 

$

14,317

 

 

$

11,722