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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Operating Expenses:    
Research and development $ 90,300 $ 73,302
General and administrative [1] 22,491 22,814
Total operating expenses 112,791 96,116
Total operating loss (112,791) (96,116)
Other income (expense):    
Interest income, including amortization and accretion income 6,631 9,429
Other income (expense) 77 (120)
Total other income 6,708 9,309
Loss before income taxes (106,083) (86,807)
Income tax provision, net (108) (112)
Net loss $ (106,191) $ (86,919)
Net loss per common share - basic $ (1.76) $ (1.75)
Net loss per common share - diluted $ (1.76) $ (1.75)
Weighted average common stock outstanding - basic 60,337,608 49,650,480
Weighted average common stock outstanding - diluted 60,337,608 49,650,480
Comprehensive loss:    
Net loss $ (106,191) $ (86,919)
Other comprehensive items:    
Unrealized loss on marketable securities (179) (271)
Currency translation adjustment (186) (5)
Total other comprehensive loss (365) (276)
Total comprehensive loss $ (106,556) $ (87,195)
[1] Includes depreciation expense directly allocated to respective activities