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Consolidated Condensed Statements of Cash Flows (Unaudited) (USD $)
6 Months Ended 278 Months Ended
Jun. 30, 2011
Jun. 30, 2010
Jun. 30, 2011
Cash flows from operating activities:      
Net loss $ (7,307,250) $ (21,841,662) $ (121,864,045)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock option compensation expense 2,208,347 1,542,685 12,986,606
Restricted stock and warrant compensation expense 253,180 1,020,198 3,809,127
Depreciation expense 456,212 175,056 988,246
Amortization of organization costs 0 0 42,165
Loss on disposal of furniture and fixtures 0 6,730 10,172
Warrant liability fair value adjustment (10,992,291) 8,053,023 9,706,311
Non-cash interest income 0 (3,051) (11,735)
Changes in assets and liabilities:      
Decrease (increase) in prepaid expenses and other assets 299,730 (163,647) (1,460,715)
Increase (decrease) in accounts payable and accrued expenses 815,718 (19,120) 4,008,028
Deferred revenue 0 300,000 300,000
Net cash used in operating activities (14,266,354) (10,891,548) (91,485,840)
Cash flows from investing activities:      
Purchase of property, plant and equipment (1,878,694) (964,276) (4,101,081)
Proceeds from sale of equipment 0 0 200
Purchase of short-term investments 0 (3,235,000) (44,646,452)
Purchase of marketable equity securities 0 0 (46,200)
Proceeds from maturities of short-term investments 1,492,000 0 44,654,356
Organization costs 0 0 (42,165)
Net cash used in investing activities (386,694) (4,199,276) (4,181,342)
Cash flows from financing activities:      
Net proceeds from sale of stock and exercise of stock options and warrants 83,167 3,458,627 125,564,428
Repurchases of common stock 0 0 (51,103)
Dividends paid on preferred stock 0 0 (499,535)
Proceeds from short-term borrowings 0 0 1,704,964
Net cash provided by financing activities 83,167 3,458,627 126,718,754
(Decrease) increase in cash and cash equivalents (14,569,881) (11,632,197) 31,051,572
Cash and cash equivalents at beginning of period 45,621,453 35,486,319 0
Cash and cash equivalents at end of period 31,051,572 23,854,122 31,051,572
Supplemental cash flow information:      
Cash paid for interest 0 0 171,473
Supplemental non-cash activities:      
Cashless exercise of stock options and shares withheld upon restricted stock vesting 61,031 424,332 1,305,625
Fair value of warrants issued 0 0 6,459,979
Fair value of warrants reclassified from liability to additional paid-in capital upon exercise $ 0 $ 8,541,937 $ 9,153,567